FUK phosphorylates beta-Fuc to Fuc1P

Stable Identifier
R-HSA-6787540
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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In the GDP-fucose salvage pathway, beta-L-fucose (beta-Fuc) arising from the turnover of glycoproteins and glycolipids in the liver and other tissues is reutilised via a two-step pathway. The first step is the phosphorylation of L-fucose (L-Fuc) to fucose-1-phosphate (Fuc1P) by L-fucose kinase (FUK) (Hinderlich et al. 2002).

Literature References
PubMed ID Title Journal Year
12056818 Identification of human L-fucose kinase amino acid sequence

Hinderlich, S, Berger, M, Blume, A, Chen, H, Ghaderi, D, Bauer, C

Biochem. Biophys. Res. Commun. 2002
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
fucokinase activity of FUK [cytosol]
Physical Entity
Activity
Orthologous Events
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