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DECR2 [peroxisomal membrane]
Stable Identifier
R-HSA-6786710
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal membrane
Synonyms
Peroxisomal 2,4-dienoyl-CoA reductase, DECR2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Peroxisomal lipid metabolism (Homo sapiens)
Beta-oxidation of very long chain fatty acids (Homo sapiens)
DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA (Homo sapiens)
DECR2 [peroxisomal membrane] (Homo sapiens)
Protein localization (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Homo sapiens)
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
DECR2 [peroxisomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NUI1 DECR2
Gene Names
DECR2, PDCR, SDR17C1
Chain
initiator methionine:, chain:2-292
Reference Genes
BioGPS Gene:26063 DECR2
COSMIC (genes):DECR2 DECR2
CTD Gene:26063 DECR2
dbSNP Gene:26063 DECR2
ENSEMBL:ENSG00000242612 DECR2
ENSEMBL_homo_sapiens_GENE:ENSG00000242612.7 DECR2
ENSEMBL_homo_sapiens_GENE:ENSG00000274296.3 DECR2
HGNC:2754 DECR2
KEGG Gene (Homo sapiens):26063 DECR2
Monarch:26063 DECR2
NCBI Gene:26063 DECR2
OMIM:615839 DECR2
UCSC:Q9NUI1 DECR2
Reference Transcript
RefSeq:NM_020664.3 DECR2
Other Identifiers
11756642_a_at
16814230
219664_PM_s_at
219664_s_at
26063
3642839
3642840
3642841
3642842
3642843
3642844
3642852
3642855
3642856
3642857
3642859
3642861
3642862
3642863
3642864
3642865
3642866
3642867
3642868
54623_at
7991846
A_23_P100315
A_33_P3393408
GE79402
GO:0003824
GO:0005515
GO:0005777
GO:0005778
GO:0005829
GO:0006629
GO:0006631
GO:0006636
GO:0008670
GO:0009062
GO:0016491
GO:0019166
GO:0033540
GO:0043226
HMNXSV003033219
ILMN_1783337
PH_hs_0028780
TC16002050.hg
g10190703_3p_a_at
Participates
as a member of
Cargo proteins containing PTS1 [peroxisomal matrix] (Homo sapiens)
Other forms of this molecule
DECR2 [cytosol]
Inferred To
NME4 [peroxisomal membrane]
(Bos taurus)
DECR2 [peroxisomal membrane]
(Canis familiaris)
DECR2 [peroxisomal membrane]
(Danio rerio)
DECR2 [peroxisomal membrane]
(Gallus gallus)
DECR2 [peroxisomal membrane]
(Mus musculus)
DECR2 [peroxisomal membrane]
(Rattus norvegicus)
DECR2 [peroxisomal membrane]
(Saccharomyces cerevisiae)
DECR2 [peroxisomal membrane]
(Sus scrofa)
Cross References
RefSeq
NP_065715.1
OpenTargets
ENSG00000242612
IntEnz
1.3.1.124
GeneCards
Q9NUI1
HPA
ENSG00000242612-DECR2
Ensembl
ENSG00000242612
,
ENSP00000488824
,
ENSP00000399697
,
ENST00000219481
,
ENSG00000274296
,
ENST00000613476
,
ENST00000439661
,
ENSP00000481547
,
ENSP00000219481
,
ENST00000631856
PRO
Q9NUI1
Pharos - Targets
Q9NUI1
HMDB Protein
HMDBP01044
PDB
4FC6
,
4FC7
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UJX0 OSGI1
0.556
3
UniProt:Q9NWQ9 CN119
0.556
3
UniProt:O14972 VP26C
0.556
3
UniProt:P51784 USP11
1
USP11 [cytosol]
(R-HSA-391303)
0.556
3
UniProt:Q8N5D0 WDTC1
1
WDTC1 [nucleoplasm]
(R-HSA-8863249)
0.499
2
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