CHIT1 hydrolyses CHIT to 3xADGP

Stable Identifier
R-HSA-6786652
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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CHIT1 hydrolyses CHIT to 3xADGP
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Chitotriose (CHIT) is an amino trisaccharide comprising of three 2-amino-2-deoxy-beta-D-glucopyranose units. Chitotriosidase-1 (CHIT1) can mediate the hydrolysis of CHIT, as well as chitin and chitobiose (Renkema et al. 1995).
Literature References
PubMed ID Title Journal Year
7836450 Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins

Renkema, GH, Boot, RG, Muijsers, AO, Donker-Koopman, WE, Aerts, JM

J. Biol. Chem. 1995
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Catalyst Activity

hydrolase activity, hydrolyzing O-glycosyl compounds of CHIT1 [extracellular region]

Physical Entity
CHIT1 [extracellular region] (Homo sapiens)
Activity
hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)
Orthologous Events
CHIT1 hydrolyses CHIT to 3xADGP (Caenorhabditis elegans)
CHIT1 hydrolyses CHIT to 3xADGP (Danio rerio)
CHIT1 hydrolyses CHIT to 3xADGP (Drosophila melanogaster)
CHIT1 hydrolyses CHIT to 3xADGP (Mus musculus)
CHIT1 hydrolyses CHIT to 3xADGP (Plasmodium falciparum)
CHIT1 hydrolyses CHIT to 3xADGP (Rattus norvegicus)
CHIT1 hydrolyses CHIT to 3xADGP (Saccharomyces cerevisiae)
CHIT1 hydrolyses CHIT to 3xADGP (Sus scrofa)
Authored
Jassal, B  (2015-07-09)
Reviewed
D'Eustachio, P  (2015-09-14)
Created
Jassal, B  (2015-07-09)
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