PUS7 transforms uridine to pseudouridine in tRNAs

Stable Identifier
R-HSA-6786583
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

As inferred from the homologue in Saccharmyces cerivisiae, PUS7 converts uridine to pseudouridine at nucleotide 13 of cytoplasmic tRNA and at nucleotide 35 of unspliced tRNA(Tyr). PUS7 also synthesizes pseudouridine in U2 snRNA and in pre-tRNA(Tyr). Pus7p is a nuclear protein according to global analysis of protein locations in yeast.

Participants
Participates
Event Information
Go Biological Process
Catalyst Activity

pseudouridine synthase activity of PUS7 [nucleoplasm]

Inferred From
Authored
Reviewed
Created
Cite Us!