p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus

Stable Identifier
R-HSA-6786293
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
Synonyms
Phosphorylated STAT3 and STAT6 dimers translocate to the nucleus
ReviewStatus
5/5
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p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus
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Phosphorylated, dimerized Signal transducer and activator of transcription 6 (STAT6) translocates to the nucleus where it regulates the expression of multiple genes (Mikita et al. 1996, Daines et al. 2003, Hebenstreit et al. 2006, Goenka & Kaplan 2011).
Literature References
PubMed ID Title Journal Year
8816495 Requirements for interleukin-4-induced gene expression and functional characterization of Stat6

Schindler, U, Campbell, D, Mikita, T, Williamson, K, Wu, P

Mol. Cell. Biol. 1996
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Orthologous Events
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Bos taurus)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Caenorhabditis elegans)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Canis familiaris)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Danio rerio)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Dictyostelium discoideum)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Drosophila melanogaster)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Gallus gallus)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Mus musculus)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Rattus norvegicus)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Sus scrofa)
p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Xenopus tropicalis)
Authored
Jupe, S  (2015-07-01)
Reviewed
Leibovich, SJ  (2016-09-02)
Created
Jupe, S  (2015-07-06)
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