Reactome | Phosphorylated ERBB2 heterodimers bind MEMO1

Phosphorylated ERBB2 heterodimers bind MEMO1

Stable Identifier

R-HSA-6785636

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol, plasma membrane

ReviewStatus

5/5

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Phosphorylated ERBB2 heterodimers bind MEMO1

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ERBB2 phosphorylated on tyrosine residue Y1222 binds MEMO1 (mediator of ERBB2-driven cell motility) (Marone et al. 2004, Qiu et al. 2008, Zaoui et al. 2010, Feracci et al. 2011).

Literature References

PubMed ID	Title	Journal	Year
20937854	ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells Zaoui, K, Benseddik, K, Salaün, D, Daou, P, Badache, A	Proc. Natl. Acad. Sci. U.S.A.	2010
21840311	MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif Feracci, M, Pimentel, C, Salaün, D, Roche, P, Guerlesquin, F, Bornet, O, Badache, A	FEBS Lett.	2011
18045866	Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site Leahy, DJ, Hynes, NE, Qiu, C, Lienhard, S, Badache, A	J. Biol. Chem.	2008
15156151	Memo mediates ErbB2-driven cell motility Dankort, D, Hess, D, Muller, WJ, Marone, R, Hynes, NE, Badache, A	Nat. Cell Biol.	2004