FANCM binds FAAP24

Stable Identifier
R-HSA-6785607
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
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FANCM binds FAAP24
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FANCM binds FAAP24, forming a complex that recognizes DNA interstrand crosslinks, thus triggering the Fanconi anemia repair pathway (Ciccia et al. 2007, Kim et al. 2008).

Literature References
PubMed ID Title Journal Year
17289582 Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM

Ciccia, A, Ling, C, Coulthard, R, Yan, Z, Xue, Y, Meetei, AR, Laghmani, el H, Joenje, H, McDonald, N, de Winter, JP, Wang, W, West, SC

Mol. Cell 2007
18174376 Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

Kim, JM, Kee, Y, Gurtan, A, D'Andrea, AD

Blood 2008
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Orthologous Events
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FANCM binds FAAP24 (Sus scrofa)
FANCM binds FAAP24 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2015-06-29)
Reviewed
Fugger, K  (2015-08-20)
Created
Orlic-Milacic, M  (2015-06-29)