FANCM binds FAAP24

Stable Identifier
R-HSA-6785607
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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FANCM binds FAAP24
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FANCM binds FAAP24, forming a complex that recognizes DNA interstrand crosslinks, thus triggering the Fanconi anemia repair pathway (Ciccia et al. 2007, Kim et al. 2008).

Literature References
PubMed ID Title Journal Year
18174376 Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

Gurtan, A, D'Andrea, AD, Kim, JM, Kee, Y

Blood 2008
17289582 Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM

West, SC, Xue, Y, de Winter, JP, Joenje, H, McDonald, N, Ling, C, Meetei, AR, Coulthard, R, Yan, Z, Laghmani, el H, Wang, W, Ciccia, A

Mol. Cell 2007
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Orthologous Events
FANCM binds FAAP24 (Bos taurus)
FANCM binds FAAP24 (Canis familiaris)
FANCM binds FAAP24 (Mus musculus)
FANCM binds FAAP24 (Rattus norvegicus)
FANCM binds FAAP24 (Sus scrofa)
Authored
Orlic-Milacic, M  (2015-06-29)
Reviewed
Fugger, K  (2015-08-20)
Created
Orlic-Milacic, M  (2015-06-29)
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