Reactome | FANCM binds FAAP24

FANCM binds FAAP24

Stable Identifier

R-HSA-6785607

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

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FANCM binds FAAP24, forming a complex that recognizes DNA interstrand crosslinks, thus triggering the Fanconi anemia repair pathway (Ciccia et al. 2007, Kim et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
17289582	Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM Ciccia, A, Ling, C, Coulthard, R, Yan, Z, Xue, Y, Meetei, AR, Laghmani, el H, Joenje, H, McDonald, N, de Winter, JP, Wang, W, West, SC	Mol. Cell	2007
18174376	Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24 Kim, JM, Kee, Y, Gurtan, A, D'Andrea, AD	Blood	2008