PCSK9 [endolysosome membrane]

Stable Identifier
R-HSA-6784823
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endolysosome membrane
Synonyms
Proprotein convertase subtilisin/kexin type 9 ecNumber3.4.21.-/ecNumber, PCSK9_HUMAN
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q8NBP7 PCSK9
Gene Names
PCSK9, NARC1, PSEC0052
Chain
signal peptide:1-30, propeptide:31-152, chain:153-692
Reference Genes
BioGPS Gene:255738 PCSK9
COSMIC (genes):PCSK9 PCSK9
CTD Gene:255738 PCSK9
dbSNP Gene:255738 PCSK9
ENSEMBL:ENSG00000169174 PCSK9
ENSEMBL_homo_sapiens_GENE:ENSG00000169174.12 PCSK9
HGNC:20001 PCSK9
KEGG Gene (Homo sapiens):255738 PCSK9
Monarch:255738 PCSK9
NCBI Gene:255738 PCSK9
OMIM:607786 PCSK9
UCSC:Q8NBP7 PCSK9
Reference Transcript
Other Identifiers
11723499_a_at
11752803_x_at
16665109
227759_PM_at
227759_at
2337419
2337420
2337421
2337422
2337423
2337424
2337425
2337426
2337429
2337430
2337431
2337432
2337433
2337434
2337435
2337436
2337438
2337439
2337440
2337441
2337443
255738
45516_at
51689_at
7901696
A_32_P142440
GE87076
GO:0001822
GO:0001889
GO:0001920
GO:0002091
GO:0002092
GO:0003723
GO:0003824
GO:0004252
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005770
GO:0005773
GO:0005783
GO:0005788
GO:0005794
GO:0005886
GO:0006508
GO:0006629
GO:0006641
GO:0006644
GO:0006915
GO:0007041
GO:0008202
GO:0008203
GO:0008233
GO:0008236
GO:0009267
GO:0009986
GO:0010469
GO:0010989
GO:0012501
GO:0016192
GO:0016485
GO:0016540
GO:0016787
GO:0019871
GO:0022008
GO:0023052
GO:0030134
GO:0030154
GO:0030163
GO:0030169
GO:0030182
GO:0030547
GO:0031232
GO:0031410
GO:0032799
GO:0032802
GO:0032803
GO:0032805
GO:0032869
GO:0034185
GO:0034189
GO:0034190
GO:0036020
GO:0042157
GO:0042632
GO:0043226
GO:0043523
GO:0043525
GO:0043621
GO:0048471
GO:0048856
GO:0050750
GO:0051604
GO:0055085
GO:0070326
GO:0098772
GO:0140096
GO:1905596
GO:1905598
GO:1905601
GO:1990666
GO:1990667
GO:2000650
HMNXSV003048870
Hs.18844.0.A1_3p_at
Hs.18844.0.A1_3p_x_at
ILMN_1668850
PH_hs_0001661
TC01000675.hg
TC01004399.hg
Participates
as a component of
Other forms of this molecule
PCSK9 [lysosomal membrane]
PCSK9 [extracellular region]
p-PCSK9 [endoplasmic reticulum lumen]
PCSK9 [endoplasmic reticulum lumen]
Inferred To
Homologues of PCSK9 [endolysosome membrane] (Saccharomyces cerevisiae)
Homologues of PCSK9 [endolysosome membrane] (Schizosaccharomyces pombe)
PCSK9 [endolysosome membrane] (Gallus gallus)
PCSK9 [endolysosome membrane] (Sus scrofa)
YSP3 [endolysosome membrane] (Saccharomyces cerevisiae)
PRB1 [endolysosome membrane] (Saccharomyces cerevisiae)
Pcsk9 [endolysosome membrane] (Mus musculus)
Pcsk9 [endolysosome membrane] (Rattus norvegicus)
isp6 [endolysosome membrane] (Schizosaccharomyces pombe)
psp3 [endolysosome membrane] (Schizosaccharomyces pombe)
RRT12 [endolysosome membrane] (Saccharomyces cerevisiae)
pcsk9 [endolysosome membrane] (Xenopus tropicalis)
Ghost homologue of PCSK9 [endolysosome membrane] (Bos taurus)
Ghost homologue of PCSK9 [endolysosome membrane] (Caenorhabditis elegans)
Ghost homologue of PCSK9 [endolysosome membrane] (Canis familiaris)
Ghost homologue of PCSK9 [endolysosome membrane] (Dictyostelium discoideum)
Ghost homologue of PCSK9 [endolysosome membrane] (Drosophila melanogaster)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
HPA
GeneCards
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (4)
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