Natriuretic peptides A (NPPA) is a hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. It specifically binds the atrial natriuretic peptide receptor 1 (NPR1) and stimulates its guanylate cyclase activity resulting in cGMP production (Koller et al. 1991, Pandey 2014).
Pandey, KN
Lowe, DG, Kangawa, K, Bennett, GL, Koller, KJ, Matsuo, H, Goeddel, DV, Minamino, N
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