Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix

Stable Identifier
R-HSA-6784213
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
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Cytosolic hydroxyproline (HPRO) is transported into the mitochonrial matrix in a saturable process distinct from the one responsible for proline uptake. The carrier that mediates this process has not been identified, however (Atlante et al. 1996).

Literature References
PubMed ID Title Journal Year
8915003 Carrier-mediated transport controls hydroxyproline catabolism in heart mitochondria from spontaneously hypertensive rat

Vulpis, V, Passarella, S, Seccia, TM, Minervini, GM, Pirrelli, A, Marra, E, Atlante, A

FEBS Lett. 1996
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Catalyst Activity

L-hydroxyproline transmembrane transporter activity of HPRO carrier [mitochondrial inner membrane]

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