Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix

Stable Identifier
R-HSA-6784213
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, mitochondrial matrix
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Unknown hydroxyproline carrier transports cytosolic HPRO into the mitochondrial matrix
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Cytosolic hydroxyproline (HPRO) is transported into the mitochonrial matrix in a saturable process distinct from the one responsible for proline uptake. The carrier that mediates this process has not been identified, however (Atlante et al. 1996).

Literature References
PubMed ID Title Journal Year
8915003 Carrier-mediated transport controls hydroxyproline catabolism in heart mitochondria from spontaneously hypertensive rat

Atlante, A, Seccia, TM, Marra, E, Minervini, GM, Vulpis, V, Pirrelli, A, Passarella, S

FEBS Lett. 1996
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
hydroxyproline transport (0034589)
Catalyst Activity
Catalyst Activity
Title
L-hydroxyproline transmembrane transporter activity of HPRO carrier [mitochondrial inner membrane]
Physical Entity
HPRO carrier [mitochondrial inner membrane]
Activity
L-hydroxyproline transmembrane transporter activity (0034590)
Authored
D'Eustachio, P  (2015-06-19)
Reviewed
Jassal, B  (2016-12-23)
Created
D'Eustachio, P  (2015-06-19)