Glycine degradation

Stable Identifier
R-HSA-6783984
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Glycine degradation
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The simplest amino acid, glycine, is catabolised by several different pathways. The major pathway is via the glycine cleavage system, comprising dimeric P protein (GLDC), T protein (AMT, GCST), dimeric L protein (DLD) and H protein (GCSH) (Kikuchi et al. 2008).

Literature References
PubMed ID Title Journal Year
18941301 Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia

Kikuchi, G, Yoshida, T, Motokawa, Y, Hiraga, K

Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. 2008
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Events
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Event Information
Go Biological Process
glycine catabolic process (0006546)
Orthologous Events
Glycine degradation (Bos taurus)
Glycine degradation (Caenorhabditis elegans)
Glycine degradation (Canis familiaris)
Glycine degradation (Danio rerio)
Glycine degradation (Dictyostelium discoideum)
Glycine degradation (Drosophila melanogaster)
Glycine degradation (Gallus gallus)
Glycine degradation (Mus musculus)
Glycine degradation (Plasmodium falciparum)
Glycine degradation (Rattus norvegicus)
Glycine degradation (Saccharomyces cerevisiae)
Glycine degradation (Schizosaccharomyces pombe)
Glycine degradation (Sus scrofa)
Glycine degradation (Xenopus tropicalis)
Authored
Jassal, B  (2015-06-18)
Reviewed
D'Eustachio, P  (2015-06-26)
Created
Jassal, B  (2015-06-18)
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