Glycine degradation

Stable Identifier
R-HSA-6783984
Type
Pathway
Species
Homo sapiens
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The simplest amino acid, glycine, is catabolised by several different pathways. The major pathway is via the glycine cleavage system, comprising dimeric P protein (GLDC), T protein (AMT, GCST), dimeric L protein (DLD) and H protein (GCSH) (Kikuchi et al. 2008).

Literature References
PubMed ID Title Journal Year
18941301 Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia

Kikuchi, G, Motokawa, Y, Yoshida, T, Hiraga, K

Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. 2008
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