As inferred from homologs in Saccharomyces cerevisiae, TYW3 transfers a methyl group from S-adenosylmethionine to yW-86 (7-((3S)-(3-amino-3-carboxypropyl))-4-demethylwyosine) at nucleotide 37 of tRNA(Phe), yielding yW-72 (7-((3S)-(3-amino-3-carboxypropyl))wyosine) and S-adenosylhomocysteine.
tRNA methyltransferase activity of TYW3 [cytoplasm]
© 2022 Reactome