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Ub-HIST1H2BJ [nucleoplasm]
Stable Identifier
R-HSA-6782566
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2BJ, Histone H2B.r
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BJ [nucleoplasm] (Homo sapiens)
USP49 deubiquitinates H2B (Homo sapiens)
USP49:Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BJ [nucleoplasm] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
RNF20:RNF40 monoubiquitinates Histone H2B (Homo sapiens)
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Ub-HIST1H2BJ [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06899 H2BC11
Gene Names
H2BC11, H2BFR, HIST1H2BJ
Chain
initiator methionine:, chain:2-126
Reference Genes
BioGPS Gene:8970 H2BC11
COSMIC (genes):HIST1H2BJ H2BC11
CTD Gene:8970 H2BC11
dbSNP Gene:8970 H2BC11
ENSEMBL:ENSG00000124635 HIST1H2BJ
HGNC:4761 H2BC11
KEGG:hsa:8970 H2BC11
Monarch:8970 H2BC11
NCBI Gene:8970 H2BC11
OMIM:615044 H2BC11
UCSC:P06899 H2BC11
Reference Transcript
RefSeq:NM_021058.3 H2BC11
Other Identifiers
11741699_at
11741700_s_at
11741701_x_at
153_f_at
17016451
2946696
2946697
2946698
2946699
2946700
2946709
2946710
2946711
2946712
3507751
8124484
85177_at
8970
A_24_P359231
A_24_P55148
GE557760
GE85150
GO:0000786
GO:0001530
GO:0002227
GO:0002376
GO:0003677
GO:0005198
GO:0005515
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0005886
GO:0006325
GO:0006334
GO:0008289
GO:0010804
GO:0019731
GO:0030527
GO:0031640
GO:0042742
GO:0043226
GO:0043229
GO:0043505
GO:0046982
GO:0050829
GO:0050830
GO:0061644
GO:0061844
GO:0065003
GO:0098542
HMNXSV003001392
ILMN_1658702
PH_hs_0035577
TC06001385.hg
TC06001386.hg
X00088_at
Participates
as a member of
Ub-histone HIST1H2B [nucleoplasm] (Homo sapiens)
Other forms of this molecule
HIST1H2BJ [nucleoplasm]
Ub-121-HIST1H2BJ [nucleoplasm]
AcK13-HIST1H2BJ [nucleoplasm]
AcK16-HIST1H2BJ [nucleoplasm]
AcK6-HIST1H2BJ [nucleoplasm]
AcK21-HIST1H2BJ [nucleoplasm]
HIST1H2BJ [extracellular region]
AcK-HIST1H2BJ [nucleoplasm]
Inferred To
H2BC11 [nucleoplasm]
(Sus scrofa)
H2Bv2 [nucleoplasm]
(Dictyostelium discoideum)
htb1 [nucleoplasm]
(Schizosaccharomyces pombe)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Ub-HIST1H2BB [nucleoplasm]
(Saccharomyces cerevisiae)
HIST1H2B5L [nucleoplasm]
(Gallus gallus)
Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
H2B-V [nucleoplasm]
(Gallus gallus)
H2Bv3 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VII [nucleoplasm]
(Gallus gallus)
Ub-HIST1H2BJ [nucleoplasm]
(Bos taurus)
Ub-HIST1H2BJ [nucleoplasm]
(Canis familiaris)
H2B-I [nucleoplasm]
(Gallus gallus)
H2bc21 [nucleoplasm]
(Mus musculus)
HTB2 [nucleoplasm]
(Saccharomyces cerevisiae)
H2Bv1 [nucleoplasm]
(Dictyostelium discoideum)
H2B-VIII [nucleoplasm]
(Gallus gallus)
His2B [nucleoplasm]
(Drosophila melanogaster)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Danio rerio)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Gallus gallus)
Homologues of Ub-HIST1H2BC [nucleoplasm]
(Xenopus tropicalis)
h2bc11 [nucleoplasm]
(Xenopus tropicalis)
si:ch211-113a14.22 [nucleoplasm]
(Danio rerio)
LOC100498553 [nucleoplasm]
(Xenopus tropicalis)
LOC116411635 [nucleoplasm]
(Xenopus tropicalis)
hist2h2l [nucleoplasm]
(Danio rerio)
HTB1 [nucleoplasm]
(Saccharomyces cerevisiae)
LOC570661 [nucleoplasm]
(Danio rerio)
h2bc21 [nucleoplasm]
(Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine (monoUb [nucleoplasm]) at 120
Coordinate
120
Modification
monoUb [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_066402.2
OpenTargets
ENSG00000124635
ENSEMBL
ENSP00000476136
,
ENSP00000342886
,
ENST00000339812
,
ENST00000607124
HPA
ENSG00000124635-H2BC11
PRO
P06899
Pharos - Targets
P06899
GlyGen
P06899
PDB
8KB5
,
8JH3
,
3AZL
,
7K63
,
8OSJ
,
6R91
,
5AV5
,
3W97
,
5X7X
,
6T90
,
7E8D
,
3AV1
,
5CPK
,
7XT7
,
8SMX
,
5B40
,
6JXD
,
6IPU
,
8SN5
,
8JLD
,
7XZX
,
6LA9
,
8OTS
,
6K1I
,
8JH2
,
5JRG
,
5XF5
,
6KVD
,
8JNF
,
3W96
,
5FUG
,
5CPI
,
7SCZ
,
6J4Y
,
6O1D
,
6IQ4
,
8HAN
,
7W9V
,
8GUK
,
5B0Y
,
6R92
,
8SN4
,
3AZE
,
8SN1
,
7D1Z
,
8UPF
,
6LA8
,
3WTP
,
7Y00
,
5B33
,
5Z23
,
3AZN
,
5Y0C
,
6K1K
,
7LYB
,
5AVC
,
3W99
,
5B24
,
3WA9
,
8JNE
,
6HKT
,
6R94
,
8YTI
,
6T93
,
6J50
,
7XSZ
,
8HAK
,
8GUI
,
6A5O
,
7XTI
,
8JLA
,
3AZG
,
6LER
,
8SMZ
,
8SN2
,
7YRD
,
8XBU
,
5GSE
,
8OTT
,
3AZM
,
7K5Y
,
8OSK
,
3W98
,
4CAY
,
7WBX
,
8I17
,
6J4W
,
8JND
,
5VEY
,
3AV2
,
6J4X
,
5GXQ
,
7XTD
,
6V2K
,
5CPJ
,
6A5L
,
8SN9
,
6M3V
,
3AZF
,
7D20
,
8SN6
,
6LA2
,
8JLB
,
8JL9
,
8XBT
,
7K5X
,
5B32
,
6INQ
,
6LAB
,
7LYA
,
5AV9
,
5AVB
,
8OSL
,
7WBW
,
8HAI
,
3AZI
,
8SN7
,
6A5R
,
5Z30
,
8HAG
,
6R8Z
,
6JR1
,
7XX6
,
4YM5
,
7C0M
,
8SN3
,
7K60
,
3AN2
,
3WAA
,
5B2J
,
5Y0D
,
7XVL
,
7COW
,
8HE5
,
7LYC
,
6K1J
,
7CCQ
,
5AV6
,
5AY8
,
7WBV
,
6JOU
,
6R93
,
6J4Z
,
6HTS
,
6A5P
,
8HAL
,
8H0V
,
8SMY
,
6E0P
,
6L4A
,
3AZH
,
6R8Y
,
7NL0
,
7XX5
,
6YOV
,
7XZY
,
8SN0
,
2RVQ
,
3A6N
,
8JH4
,
6L49
,
6USJ
,
7VCL
,
7VZ4
,
8RBX
,
5XF3
,
5GTC
,
6E0C
,
6J51
,
3AZK
,
7XSX
,
6A5T
,
8SN8
,
8HAM
,
8QKT
,
8HAH
,
8SNA
,
6M44
,
8GUJ
,
6IR9
,
6L9Z
,
7XZZ
,
8G57
,
5B31
,
7Y7I
,
5ZBX
,
8IHL
,
7CCR
,
5AV8
,
5XF4
,
7ZI4
,
7BY0
,
7SCY
,
6BUZ
,
8HAJ
,
6A5U
,
8SMW
,
3AZJ
,
8H0W
,
4Z5T
,
5B0Z
,
3AYW
,
4YM6
,
6JR0
,
6R90
,
8U14
,
7XSE
,
6KXV
,
7K61
,
3AFA
,
5B2I
,
7XVM
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
2
UniProt:P02675 FGB
5
FGB [extracellular region]
(R-HSA-140584)
FGB(31-44) [extracellular region]
(R-HSA-140876)
FGB [plasma membrane]
(R-HSA-140917)
FGB(31-491) [extracellular region]
(R-HSA-140846)
FGB(31-491) [platelet alpha granule lumen]
(R-HSA-140921)
0.527
2
UniProt:P68871 HBB
8
HBB [lysosomal lumen]
(R-HSA-9625193)
HBB [cytosol]
(R-HSA-1008196)
HBB [late endosome lumen]
(R-HSA-9631108)
HBB [tertiary granule lumen]
(R-HSA-6800191)
HBB [extracellular region]
(R-HSA-2168872)
HBB [ficolin-1-rich granule lumen]
(R-HSA-6801015)
HBB [endocytic vesicle lumen]
(R-HSA-2230936)
CO-H+-HBB [cytosol]
(R-HSA-1237013)
0.527
2
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