Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TRMT1 [nucleoplasm]
Stable Identifier
R-HSA-6782450
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
tRNA 2,2-dimethylguanosine-26 methyltransferase, TRM1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) (Homo sapiens)
TRMT1 [nucleoplasm] (Homo sapiens)
General
Location in nucleus inferred from yeast homolog
External Reference Information
External Reference
UniProt:Q9NXH9 TRMT1
Gene Names
TRMT1
Chain
chain:1-659
Reference Genes
BioGPS Gene:55621 TRMT1
COSMIC (genes):TRMT1 TRMT1
CTD Gene:55621 TRMT1
dbSNP Gene:55621 TRMT1
ENSEMBL:ENSG00000104907 TRMT1
HGNC:25980 TRMT1
Monarch:55621 TRMT1
NCBI Gene:55621 TRMT1
OMIM:611669 TRMT1
UCSC:Q9NXH9 TRMT1
Reference Transcript
RefSeq:NM_001142554.1 TRMT1
RefSeq:XM_017026944.1 TRMT1
RefSeq:NM_017722.3 TRMT1
RefSeq:XM_017026945.1 TRMT1
RefSeq:NM_001136035.2 TRMT1
Other Identifiers
11757352_a_at
16869397
203701_PM_s_at
203701_s_at
210463_PM_x_at
210463_x_at
32096_at
3852033
3852035
3852036
3852037
3852038
3852039
3852040
3852041
3852042
3852043
3852044
3852045
3852046
3852047
3852048
3852049
3852050
3852051
3852053
3852054
3852055
3852056
3852057
3852058
3852059
3852060
3852061
3852062
3852063
3852064
3852065
3852066
3852067
3852068
3852069
3993816
3993818
3993825
55621
71211_at
8034615
A_23_P16683
GE55415
GE587208
GO:0000049
GO:0002940
GO:0003723
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005739
GO:0006399
GO:0006400
GO:0008033
GO:0008168
GO:0016740
GO:0032259
GO:0043226
GO:0046872
GO:0140098
GO:0160102
GO:0160104
HMNXSV003037798
ILMN_1812940
PH_hs_0024873
PH_hs_0035925
TC19001218.hg
g12803346_3p_a_at
Cross References
ENSEMBL
ENSP00000221504
,
ENST00000221504
,
ENSP00000466967
,
ENSP00000350352
,
ENST00000437766
,
ENSP00000416149
,
ENST00000357720
,
ENST00000592062
OpenTargets
ENSG00000104907
HPA
ENSG00000104907-TRMT1
PRO
Q9NXH9
Pharos - Targets
Q9NXH9
GlyGen
Q9NXH9
Orphanet
TRMT1
HMDB Protein
HMDBP09045
PDB
8D35
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P43364 MAGAB
0.742
5
UniProt:P43364-2 MAGEA11
0.556
3
UniProt:P0DTD1-PRO_0000449623 REP
0.527
2
UniProt:P54274 TERF1
1
TERF1 [nucleoplasm]
(R-HSA-164618)
0.508
2
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text