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ZRANB1 [cytosol]
Stable Identifier
R-HSA-6781939
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin thioesterase ZRANB1, ZRAN1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q96SQ5 ZNF587
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ovarian tumor domain proteases (Homo sapiens)
ZRANB1 binds APC (Homo sapiens)
ZRANB1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
ZRANB1 binds APC (Homo sapiens)
ZRANB1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UGI0 ZRANB1
Gene Names
ZRANB1, TRABID
Chain
chain:1-708
Reference Genes
BioGPS Gene:54764 ZRANB1
COSMIC (genes):ZRANB1 ZRANB1
CTD Gene:54764 ZRANB1
dbSNP Gene:54764 ZRANB1
ENSEMBL:ENSG00000019995 ZRANB1
ENSEMBL_homo_sapiens_GENE:ENSG00000019995.6 ZRANB1
HGNC:18224 ZRANB1
KEGG Gene (Homo sapiens):54764 ZRANB1
Monarch:54764 ZRANB1
NCBI Gene:54764 ZRANB1
OMIM:611749 ZRANB1
UCSC:Q9UGI0 ZRANB1
Reference Transcript
RefSeq:XM_017016357.1 ZRANB1
RefSeq:NM_017580.2 ZRANB1
RefSeq:XM_005269926.4 ZRANB1
Other Identifiers
11727497_x_at
11727498_at
11727499_s_at
11758596_s_at
11758984_at
16710360
225130_PM_at
225130_at
225131_PM_at
225131_at
225138_PM_at
225138_at
3269341
3269342
3269343
3269344
3269355
3269358
3269359
3269361
3269366
3269368
3269369
3269376
3269377
3269378
3269379
3269380
3269381
3269382
3269383
3269385
3269387
3370743
43473_at
49688_at
54764
61267_at
65838_s_at
7931226
83098_at
A_14_P105497
A_14_P117940
A_24_P389714
A_24_P9809
A_33_P3261565
GE55302
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006508
GO:0007010
GO:0008233
GO:0008234
GO:0016055
GO:0016477
GO:0016787
GO:0022604
GO:0023052
GO:0030163
GO:0030177
GO:0031593
GO:0035523
GO:0036211
GO:0043226
GO:0043231
GO:0046872
GO:0048856
GO:0048870
GO:0070530
GO:0070536
GO:0071947
GO:0101005
GO:0140096
GO:1990168
HMNXSV003009721
Hs.26320.0.S1_3p_at
Hs.26320.0.S2_3p_at
Hs.26320.0.S3_3p_at
ILMN_1757742
PH_hs_0002321
TC10000909.hg
p33382
Participates
as a member of
OTUD7B,TNFAIP3,ZRANB1 [cytosol] (Homo sapiens)
as a component of
ZRANB1:K63polyUb-APC [cytosol] (Homo sapiens)
as an input of
ZRANB1 binds APC (Homo sapiens)
Inferred To
trbd [cytosol]
(Drosophila melanogaster)
ZRANB1 [cytosol]
(Bos taurus)
ZRANB1 [cytosol]
(Canis familiaris)
ZRANB1 [cytosol]
(Danio rerio)
ZRANB1 [cytosol]
(Gallus gallus)
ZRANB1 [cytosol]
(Mus musculus)
ZRANB1 [cytosol]
(Sus scrofa)
ZRANB1 [cytosol]
(Xenopus tropicalis)
Zranb1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_060050.2
,
XP_016871846.1
,
XP_005269983.1
OpenTargets
ENSG00000019995
HPA
ENSG00000019995-ZRANB1
GeneCards
Q9UGI0
Ensembl
ENST00000359653
,
ENSP00000352676
,
ENSG00000019995
PRO
Q9UGI0
Pharos - Targets
Q9UGI0
PDB
5AF6
,
3ZRH
Interactors (144)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P30039 PBLD
0.756
6
UniProt:Q9Y4K3 TRAF6
8
K48polyUb-TRAF6 [cytosol]
(R-HSA-6783233)
PolyUb-TRAF6 [cytosol]
(R-HSA-6782845)
TRAF6 [endosome membrane]
(R-HSA-450272)
K63polyUb-TRAF6 [endosome membrane]
(R-HSA-450227)
TRAF6 [cytosol]
(R-HSA-166366)
K63polyUb-TRAF6 [cytosol]
(R-HSA-2685681)
K63polyUb-TRAF6 [plasma membrane]
(R-HSA-936980)
TRAF6 [plasma membrane]
(R-HSA-936955)
0.675
4
UniProt:P53582 METAP1
1
METAP1 [cytosol]
(R-HSA-2534097)
0.601
4
UniProt:P0CG48 UBC
20
UBC(381-456) [endocytic vesicle membrane]
(R-HSA-939218)
UBC(533-608) [endocytic vesicle membrane]
(R-HSA-939220)
UBC(609-684) [endocytic vesicle membrane]
(R-HSA-939223)
UBC(457-532) [endocytic vesicle membrane]
(R-HSA-939195)
UBC(153-228) [endocytic vesicle membrane]
(R-HSA-939194)
UBC(305-380) [endocytic vesicle membrane]
(R-HSA-939228)
UBC(229-304) [endocytic vesicle membrane]
(R-HSA-939177)
UBC(77-152) [endocytic vesicle membrane]
(R-HSA-939210)
UBC(1-76) [endocytic vesicle membrane]
(R-HSA-939245)
Ub-565-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783166)
Ub-337-UBC(305-380) [mitochondrial outer membrane]
(R-HSA-6783121)
Ub-185-UBC(153-228) [mitochondrial outer membrane]
(R-HSA-6783154)
Ub-261-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783028)
Ub-413-UBC(381-456) [mitochondrial outer membrane]
(R-HSA-6783061)
Ub-109-UBC(77-152) [mitochondrial outer membrane]
(R-HSA-6783158)
Ub-641-UBC(609-684) [mitochondrial outer membrane]
(R-HSA-6783182)
Ub-33-UBC(1-76) [mitochondrial outer membrane]
(R-HSA-6783073)
Ub-489-UBC(457-532) [mitochondrial outer membrane]
(R-HSA-6783078)
Ub-291-UBC(229-304) [mitochondrial outer membrane]
(R-HSA-6783193)
Ub-595-UBC(533-608) [mitochondrial outer membrane]
(R-HSA-6783130)
0.558
2
UniProt:Q15287 RNPS1
2
RNPS1 [nucleoplasm]
(R-HSA-156778)
RNPS1 [cytosol]
(R-HSA-159256)
0.556
3
UniProt:P13010 XRCC5
4
XRCC5 [extracellular region]
(R-HSA-6806530)
XRCC5 [secretory granule lumen]
(R-HSA-6801297)
XRCC5 [cytosol]
(R-HSA-3134849)
XRCC5 [nucleoplasm]
(R-HSA-58274)
0.556
3
UniProt:Q15560 TCEA2
0.556
3
UniProt:Q9Y2I9-2 Q9Y2I92
0.556
3
UniProt:Q3KQV3 ZNF792
1
ZNF792 [nucleoplasm]
(R-HSA-3110242)
0.556
3
UniProt:P57075-2 UBASH3A
0.556
3
UniProt:Q9BSW7 SYT17
0.556
3
UniProt:Q8IVT4 Q8IVT4
0.556
3
UniProt:Q96C24 SYTL4
2
SYTL4 [platelet alpha granule membrane]
(R-HSA-8862959)
SYTL4 [plasma membrane]
(R-HSA-8862971)
0.556
3
UniProt:O75564-2 O755642
0.556
3
IntAct:EBI-22335676 CCSB ORF ID
0.556
3
UniProt:Q6ZNH5 ZN497
0.556
3
UniProt:Q9UK58 CCNL1
0.556
3
UniProt:Q86XF7 ZN575
0.556
3
UniProt:O00560 SDCBP
3
SDCBP [extracellular region]
(R-HSA-6806206)
SDCBP [azurophil granule lumen]
(R-HSA-6799372)
SDCBP [cytosol]
(R-HSA-373639)
0.556
3
UniProt:P61326 MAGOH
1
MAGOH [nucleoplasm]
(R-HSA-156658)
0.556
3
UniProt:Q9H0I2 ENKD1
0.556
3
UniProt:O95696 BRD1
1
BRD1 [nucleoplasm]
(R-HSA-3318450)
0.556
3
UniProt:Q9BVV2 FND11
0.556
3
UniProt:Q96EG3 ZN837
0.556
3
UniProt:Q14119 VEZF1
0.556
3
UniProt:Q9HC52 CBX8
1
CBX8 [nucleoplasm]
(R-HSA-389117)
0.556
3
UniProt:Q08117-2 TLE5
0.556
3
UniProt:Q96BZ8 LENG1
1
LENG1 [nucleoplasm]
(R-HSA-9769590)
0.556
3
UniProt:Q9BZE0 GLIS2
0.556
3
UniProt:O43189 PHF1
1
PHF1 [nucleoplasm]
(R-HSA-5084105)
0.556
3
UniProt:O43463 SUV39H1
1
SUV39H1 [nucleoplasm]
(R-HSA-427517)
0.556
3
UniProt:Q6NYC8 PPR18
0.556
3
UniProt:P59910 DJB13
0.556
3
UniProt:P26196 DDX6
1
DDX6 [cytosol]
(R-HSA-430032)
0.556
3
UniProt:Q9UFB7 ZBT47
0.556
3
UniProt:Q8NE01 CNNM3
0.556
3
UniProt:O15371 EIF3D
1
EIF3D [cytosol]
(R-HSA-72548)
0.556
3
UniProt:P19544-6 WT1
0.556
3
UniProt:Q9NVQ4-2 FAIM
0.556
3
UniProt:B7ZLI8 B7ZLI8
0.556
3
UniProt:Q07002 CDK18
0.556
3
UniProt:Q96B67 ARRD3
0.556
3
UniProt:P0DI81-3 TRAPPC2
0.556
3
UniProt:Q8N8B7-2 TCEANC
0.556
3
UniProt:Q9BRJ7 TIRR
0.556
3
UniProt:Q8TAP4-4 LMO3
0.556
3
UniProt:Q96HB5 CC120
0.556
3
UniProt:P55040 GEM
1
GEM [plasma membrane]
(R-HSA-9769962)
0.556
3
UniProt:Q96SQ5 ZNF587
1
ZNF587 [nucleoplasm]
(R-HSA-2127565)
0.556
3
UniProt:P09067 HXB5
0.556
3
UniProt:O15442-2 MPPED1
0.556
3
UniProt:Q9UBL6-2 CPNE7
0.556
3
UniProt:O60941-5 DTNB
0.556
3
UniProt:Q9BUZ4 TRAF4
0.556
3
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.556
3
UniProt:O15481 MAGB4
0.556
3
UniProt:P50548 ERF
3
p-T526-ERF [nucleoplasm]
(R-HSA-3209166)
p-T526-ERF [cytosol]
(R-HSA-3209167)
ERF [nucleoplasm]
(R-HSA-2534321)
0.556
3
UniProt:O43809 NUDT21
1
NUDT21 [nucleoplasm]
(R-HSA-72010)
0.556
3
UniProt:Q3SY00 T10IP
0.556
3
UniProt:Q92917 GPKOW
1
GPKOW [nucleoplasm]
(R-HSA-8850839)
0.556
3
UniProt:P47897 QARS1
2
QARS [cytosol]
(R-HSA-379615)
QARS [mitochondrial matrix]
(R-HSA-379592)
0.556
3
UniProt:P15622-3 ZNF250
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:Q8NHY3 GA2L2
0.556
3
UniProt:Q9UII6 DS13B
0.556
3
UniProt:X5D778 X5D778
0.556
3
UniProt:Q96PC2 IP6K3
1
IP6K3 [cytosol]
(R-HSA-1604594)
0.556
3
UniProt:Q16512 PKN1
3
p-T774-PKN1 [nucleoplasm]
(R-HSA-5625721)
p-T774-PKN1 [cytosol]
(R-HSA-5623651)
PKN1 [cytosol]
(R-HSA-5623613)
0.556
3
UniProt:Q8IYE1 CCD13
0.556
3
UniProt:Q3B820 F161A
0.556
3
UniProt:Q2TBE0 CWF19L2
1
CWF19L2 [nucleoplasm]
(R-HSA-9770846)
0.556
3
UniProt:Q8TAE8 GADD45GIP1
1
GADD45GIP1 [mitochondrial matrix]
(R-HSA-5368253)
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:Q96NL3 ZNF599
1
ZNF599 [nucleoplasm]
(R-HSA-2127571)
0.556
3
UniProt:Q8WUT1 Q8WUT1
0.556
3
UniProt:Q5T6S3 PHF19
1
PHF19 [nucleoplasm]
(R-HSA-5084115)
0.556
3
UniProt:Q9P2K5-2 MYEF2
0.556
3
UniProt:Q08426 EHHADH
2
EHHADH [peroxisomal matrix]
(R-HSA-400155)
EHHADH [cytosol]
(R-HSA-9033147)
0.556
3
UniProt:Q9P0T4 ZN581
0.556
3
UniProt:O75419 CDC45
1
CDC45 [nucleoplasm]
(R-HSA-68563)
0.556
3
UniProt:Q9H707 ZNF552
1
ZNF552 [nucleoplasm]
(R-HSA-1973877)
0.556
3
UniProt:Q9UJV3-2 MID2
0.556
3
UniProt:Q96H86 ZNF764
1
ZNF764 [nucleoplasm]
(R-HSA-3343766)
0.556
3
UniProt:Q9H257-2 CARD9
0.556
3
UniProt:Q9Y247 FA50B
0.556
3
UniProt:Q9HC98-4 NEK6
0.556
3
UniProt:P17021 ZNF17
1
ZNF17 [nucleoplasm]
(R-HSA-974984)
0.556
3
UniProt:Q6DHY5 TBC3G
0.556
6
UniProt:Q8WWY3 PRPF31
1
PRPF31 [nucleoplasm]
(R-HSA-6806772)
0.556
3
UniProt:Q8TBH0 ARRD2
0.556
3
UniProt:O95931 CBX7
0.556
3
UniProt:Q9BU76 MMTAG2
3
MMTAG2 [secretory granule lumen]
(R-HSA-6801073)
MMTAG2 [extracellular region]
(R-HSA-6806452)
MMTAG2 [ficolin-1-rich granule lumen]
(R-HSA-6801074)
0.556
3
UniProt:Q9BT49 THAP7
0.556
3
UniProt:Q5T619 ZN648
0.556
3
UniProt:Q9UEG4 ZN629
0.556
3
UniProt:Q494U1-3 PLEKHN1
0.556
3
UniProt:Q96BV0 ZNF775
1
ZNF775 [nucleoplasm]
(R-HSA-3110230)
0.556
3
UniProt:Q9ULM2 ZNF490
1
ZNF490 [nucleoplasm]
(R-HSA-1247870)
0.556
3
UniProt:P0DTD1-PRO_0000449633 REP
0.556
3
UniProt:Q12774 ARHGEF5
1
ARHGEF5 [cytosol]
(R-HSA-8873909)
0.556
3
UniProt:Q9UJ04 TSYL4
0.556
3
UniProt:Q8WXF1-2 PSPC1
0.556
3
UniProt:Q99459 CDC5L
1
CDC5L [nucleoplasm]
(R-HSA-5420887)
0.556
3
UniProt:Q9C086 INO80B
1
INO80B [nucleoplasm]
(R-HSA-5689599)
0.556
3
UniProt:Q5T7W7 TSTD2
0.556
3
UniProt:Q96FJ0 STAMBPL1
1
STAMBPL1 [cytosol]
(R-HSA-6783264)
0.556
3
UniProt:A6NER0 TBC3F
0.556
3
UniProt:Q96PV4 PNMA5
0.556
3
UniProt:Q8TBE0 BAHD1
0.556
3
UniProt:O94955 RHOBTB3
1
RHOBTB3 [trans-Golgi network membrane]
(R-HSA-6813908)
0.556
3
UniProt:Q8NA54 IQUB
0.556
3
UniProt:Q9Y228 T3JAM
0.556
3
UniProt:O43602-2 DCX
0.556
3
UniProt:Q15973 ZNF124
1
ZNF124 [nucleoplasm]
(R-HSA-975017)
0.556
3
UniProt:Q9H5Z6-2 FAM124B
0.556
3
UniProt:Q14005-2 Q140052
0.556
3
UniProt:Q8N715 CC185
0.556
3
UniProt:O43395 PRPF3
1
PRPF3 [nucleoplasm]
(R-HSA-6806806)
0.556
3
UniProt:P35590 TIE1
0.556
3
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.556
3
UniProt:Q63ZY3 KANK2
0.556
3
UniProt:O95872 GPAN1
0.556
3
UniProt:O15160 POLR1C
2
POLR1C [nucleoplasm]
(R-HSA-63498)
POLR1C [cytosol]
(R-HSA-1964454)
0.556
3
UniProt:Q96MY7 F161B
0.556
3
UniProt:Q9UGP5-2 POLL
0.556
3
UniProt:Q9BXS5 AP1M1
7
AP1M1 [cytoplasmic vesicle membrane]
(R-HSA-351196)
AP1M1 [Golgi membrane]
(R-HSA-350805)
AP1M1 [lysosomal membrane]
(R-HSA-432708)
AP1M1 [trans-Golgi network membrane]
(R-HSA-2130512)
AP1M1 [cytosol]
(R-HSA-167700)
AP1M1 [plasma membrane]
(R-HSA-6806311)
AP1M1 [specific granule membrane]
(R-HSA-6799365)
0.556
3
UniProt:Q8IVW4 CDKL3
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.556
3
UniProt:Q9UKW4 VAV3
2
VAV3 [cytosol]
(R-HSA-430152)
p-Y173-VAV3 [cytosol]
(R-HSA-442287)
0.556
3
UniProt:Q9H0E2 TOLLIP
4
TOLLIP [cytosol]
(R-HSA-446885)
TOLLIP [azurophil granule lumen]
(R-HSA-6799709)
TOLLIP [extracellular region]
(R-HSA-6800448)
TOLLIP [specific granule lumen]
(R-HSA-6799719)
0.556
3
UniProt:Q8WXB1 METTL21A
1
METTL21A [nucleoplasm]
(R-HSA-8876682)
0.556
3
UniProt:Q9HAQ2 KIF9
1
KIF9 [cytosol]
(R-HSA-984616)
0.556
3
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.556
3
UniProt:Q7L5A3 ATOSB
0.556
3
UniProt:Q7Z4V0 ZN438
0.556
3
UniProt:O43167 ZBT24
0.556
3
UniProt:Q8IZW8 TNS4
1
TNS4 [cytosol]
(R-HSA-201624)
0.556
3
UniProt:Q9H9D4 ZN408
0.556
3
UniProt:Q8TAU3 ZNF417
1
ZNF417 [nucleoplasm]
(R-HSA-1247539)
0.556
3
UniProt:Q86YV0 RASAL3
1
RASAL3 [cytosol]
(R-HSA-5658226)
0.556
3
UniProt:Q96EZ8 MCRS1
1
MCRS1 [nucleoplasm]
(R-HSA-3321849)
0.556
3
UniProt:Q96IQ9 ZN414
0.527
2
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