Reactome | TAF1 [nucleoplasm]

TAF1 [nucleoplasm]

Stable Identifier

R-HSA-65539

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription initiation factor TFIID 250 kDa subunit, TAFII-250, TAFII250, TBP-associated factor 250 kDa, P250, Cell cycle gene 1 protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P21675 TAF1

Gene Names

TAF1, BA2R, CCG1, CCGS, TAF2A

Chain

chain:1-1893

Reference Genes

BioGPS Gene:6872 TAF1

COSMIC (genes):TAF1 TAF1

CTD Gene:6872 TAF1

dbSNP Gene:6872 TAF1

ENSEMBL:ENSG00000147133 TAF1

HGNC:11535 TAF1

KEGG:hsa:6872 TAF1

Monarch:6872 TAF1

NCBI Gene:6872 TAF1

OMIM:313650 TAF1

UCSC:P21675 TAF1

Reference Transcript

Other Identifiers

112_g_at

11723629_a_at

11756116_a_at

216711_PM_s_at

216711_s_at

227205_PM_at

227205_at

3203204

3203206

3203207

3203210

3203212

3203213

3203215

37491_at

3981028

3981029

3981030

3981032

3981033

3981037

3981038

3981040

3981041

3981042

3981043

3981044

3981045

3981046

3981048

3981049

3981050

3981051

3981052

3981053

3981054

3981055

3981056

3981057

3981058

3981059

3981060

3981061

3981062

3981063

3981064

3981065

3981067

3981068

3981070

3981071

3981072

3981076

3981078

3981079

3981080

3981081

3981082

3981087

3981088

3981091

3981092

3981093

3981094

3981095

3981096

3981097

3981099

3981100

3981101

3981102

3981103

3981104

3981105

3981106

3981107

3981108

3981109

3981114

3981115

3981116

3981117

3981118

3981119

3981121

3981122

3981123

3981124

62571_at

6872

8168303

A_14_P139152

A_23_P11237

A_32_P192615

A_33_P3353111

D90359_at

GE79129

GO:0000122

GO:0000209

GO:0000785

GO:0000979

GO:0001091

GO:0001181

GO:0002039

GO:0003677

GO:0003824

GO:0004402

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005667

GO:0005669

GO:0005730

GO:0006325

GO:0006338

GO:0006351

GO:0006352

GO:0006355

GO:0006361

GO:0006366

GO:0006367

GO:0006468

GO:0006511

GO:0006974

GO:0010629

GO:0016071

GO:0016251

GO:0016301

GO:0016740

GO:0016746

GO:0016922

GO:0017025

GO:0018105

GO:0018107

GO:0030901

GO:0032092

GO:0032436

GO:0034644

GO:0042393

GO:0042789

GO:0043226

GO:0043565

GO:0045944

GO:0046777

GO:0046982

GO:0048856

GO:0050821

GO:0051123

GO:0060090

GO:0060261

GO:0061628

GO:0061629

GO:0061631

GO:0061733

GO:0065003

GO:0070577

GO:0071318

GO:0071339

GO:0098772

GO:0106310

GO:0140096

GO:0140223

GO:0140416

GO:0140566

GO:1901796

GO:1902806

GO:1905524

GO:2000059

GO:2000825

HMNXSV003011716

HMNXSV003018921

HMNXSV003043765

HMNXSV003053463

HMNXSV003054755

Hs.1179.1.A1_3p_at

Hs.1179.3.S1_3p_a_at

ILMN_1664439

ILMN_2346358

PH_hs_0000155

TC0X000387.hg

Participates

as a member of

TAF1,TAF1L [nucleoplasm] (Homo sapiens)

Inferred To

taf1 [nucleoplasm] (Dictyostelium discoideum)

taf1 [nucleoplasm] (Xenopus tropicalis)

taf-1 [nucleoplasm] (Caenorhabditis elegans)

Taf1 [nucleoplasm] (Drosophila melanogaster)

Taf1 [nucleoplasm] (Mus musculus)

Taf1 [nucleoplasm] (Rattus norvegicus)

TAF1 [nucleoplasm] (Bos taurus)

TAF1 [nucleoplasm] (Canis familiaris)

TAF1 [nucleoplasm] (Gallus gallus)

TAF1 [nucleoplasm] (Saccharomyces cerevisiae)

TAF1 [nucleoplasm] (Schizosaccharomyces pombe)

TAF1 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_620278.1, NP_001273003.1, NP_004597.2, XP_005262352.1

Guide to Pharmacology - Targets

2231

OpenTargets

ENSG00000147133

ENSEMBL

ENSP00000362895, ENST00000373790, ENSP00000406549, ENST00000423759

ZINC - Substances

TAF1_HUMAN

ZINC target

P21675

PRO

P21675

GlyGen

P21675

PDB

7JJH, 7JJG, 4YYM, 7K03, 7EGJ, 5I29, 6MZD, 6P3A, 7EGC, 6MZM, 7EGA, 7EG9, 8WAS, 5FUR, 7T2I, 8WAP, 4RGW, 7K0U, 7LB1, 7LB0, 7K1P, 7K27, 8WAL, 8WAK, 8WAR, 3AAD, 5MG2, 7EG8, 7EGH, 3UV4, 7T36, 3UV5, 7K6F, 6BQD, 6FIC, 6MZL, 7K3O, 7K42, 7EGD, 7EGB, 6P39, 4YYN, 5I1Q, 8GXS, 8GXQ, 7EGI, 8WAN, 8WAQ, 8WAO, 7L6X, 7LB3, 7LB2, 7N42, 7K0D, 6P38, 7EDX, 7JSP, 7EG7, 7JTC, 1EQF, 7P4S, 7EGE, 7ENC, 7ENA

IntEnz

2.3.1.48

HPA

ENSG00000147133-TAF1

Pharos - Targets

P21675

Orphanet

TAF1

ZINC - Predictions - Purchasable

TAF1_HUMAN

HMDB Protein

HMDBP08821

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P20226 TBP	1	TBP [nucleoplasm] (R-HSA-83718)	0.895	11
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.553	2

Cite Us!