Reactome | POLR2H [nucleoplasm]

POLR2H [nucleoplasm]

Stable Identifier

R-HSA-63523

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide , RPB17, RPB8, RPABC3

Locations in the PathwayBrowser for interactor UniProt:O95602 POLR1A

Expand all

External Reference Information

External Reference

UniProt:P52434 POLR2H

Gene Names

POLR2H

Chain

initiator methionine:, chain:2-150

Reference Genes

BioGPS Gene:5437 POLR2H

COSMIC (genes):POLR2H POLR2H

CTD Gene:5437 POLR2H

dbSNP Gene:5437 POLR2H

ENSEMBL:ENSG00000163882 POLR2H

ENSEMBL_homo_sapiens_GENE:ENSG00000163882.10 POLR2H

HGNC:9195 POLR2H

KEGG Gene (Homo sapiens):5437 POLR2H

Monarch:5437 POLR2H

NCBI Gene:5437 POLR2H

OMIM:606023 POLR2H

UCSC:P52434 POLR2H

Reference Transcript

Other Identifiers

11721282_a_at

1248_at

16948989

209302_PM_at

209302_at

2655774

2655775

2655776

2655777

2655778

2655780

2655782

2655785

2655787

2655788

2655789

35631_at

5437

8084488

A_23_P29803

A_33_P3396459

GE59118

GO:0000428

GO:0001054

GO:0001055

GO:0001056

GO:0003677

GO:0003697

GO:0003824

GO:0003899

GO:0005634

GO:0005654

GO:0005665

GO:0005666

GO:0005730

GO:0005736

GO:0005829

GO:0006351

GO:0006360

GO:0006366

GO:0006383

GO:0016740

GO:0032993

GO:0043226

GO:0043229

GO:0140098

HMNXSV003050215

ILMN_1689445

PH_hs_0020014

TC03001003.hg

U37689_at

g1017822_3p_at

Participates

as a component of

as an input of

Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)

Other forms of this molecule

POLR2H [cytosol]

Inferred To

rpb-8 [nucleoplasm] (Caenorhabditis elegans)

Polr2H [nucleoplasm] (Drosophila melanogaster)

rpb8 [nucleoplasm] (Schizosaccharomyces pombe)

POLR2H [nucleoplasm] (Bos taurus)

POLR2H [nucleoplasm] (Canis familiaris)

POLR2H [nucleoplasm] (Gallus gallus)

POLR2H [nucleoplasm] (Plasmodium falciparum)

POLR2H [nucleoplasm] (Sus scrofa)

Polr2h [nucleoplasm] (Mus musculus)

RPB8 [nucleoplasm] (Saccharomyces cerevisiae)

polr2h [nucleoplasm] (Danio rerio)

polr2h [nucleoplasm] (Dictyostelium discoideum)

polr2h [nucleoplasm] (Xenopus tropicalis)

LOC120098305 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001265643.1, NP_001265629.1, XP_016862126.1, XP_006713730.1, XP_006713729.1, XP_016862125.1, NP_001265628.1, NP_006223.2, NP_001265644.1, NP_001265627.1

OpenTargets

ENSG00000163882

HPA

ENSG00000163882-POLR2H

GeneCards

P52434

Ensembl

ENSP00000411883, ENST00000430783, ENSP00000399882, ENSP00000415536, ENST00000438240, ENST00000452961, ENSP00000393773, ENST00000456318, ENST00000443489, ENSG00000163882, ENSP00000398622, ENSP00000392913, ENST00000429568

PRO

P52434

Pharos - Targets

P52434

HMDB Protein

HMDBP11913

PDB

6O9L, 7D59, 5IY7, 7OBA, 7DN3, 7LBM, 8ITY, 5IY8, 7AE1, 5IY9, 7OBB, 7AE3, 7VBA, 2F3I, 8IUE, 6XRE, 5IYA, 7DU2, 8IUH, 7VBB, 7FJI, 5IYB, 7VBC, 8A43, 5IYC, 7AEA, 7FJJ, 5IYD, 7OB9, 6DRD, 7AST, 7D58, 7A6H, 5IY6

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19388 POLR2E	2	POLR2E [nucleoplasm] (R-HSA-83713) POLR2E [cytosol] (R-HSA-1964438)	0.772	7
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.643	4
UniProt:Q9Y2Y1 POLR3K	2	POLR3K [nucleoplasm] (R-HSA-1964461) POLR3K [cytosol] (R-HSA-1964455)	0.527	2
UniProt:P52435 POLR2J	1	POLR2J [nucleoplasm] (R-HSA-63531)	0.527	4
UniProt:P19387 POLR2C	1	POLR2C [nucleoplasm] (R-HSA-63506)	0.527	3
UniProt:Q9Y535 POLR3H	2	POLR3H [nucleoplasm] (R-HSA-83710) POLR3H [cytosol] (R-HSA-1964440)	0.527	4
UniProt:O15514 POLR2D	1	POLR2D [nucleoplasm] (R-HSA-63508)	0.527	2
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.527	2
UniProt:P0CAP2 GRL1A			0.527	2
UniProt:O95602 POLR1A	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.527	2
UniProt:O15160 POLR1C	2	POLR1C [nucleoplasm] (R-HSA-63498) POLR1C [cytosol] (R-HSA-1964454)	0.527	3
UniProt:Q8IXW5 RPAP2	1	RPAP2 [nucleoplasm] (R-HSA-6810227)	0.527	2
UniProt:P62875 POLR2L	2	POLR2L [nucleoplasm] (R-HSA-83715) POLR2L [cytosol] (R-HSA-1964467)	0.527	2
UniProt:P61218 POLR2F	2	POLR2F [nucleoplasm] (R-HSA-83714) POLR2F [cytosol] (R-HSA-1964441)	0.527	4
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	3

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