ATIC [cytosol]

Stable Identifier
R-HSA-62506
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase, Bifunctional purine biosynthesis protein PURH (Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (Inosinicase) (IMP synthetase) (ATIC)), Bifunctional purine biosynthesis protein PURH, Phosphoribosylaminoimidazolecarboxamide formyltransferase , AICAR transformylase, IMP cyclohydrolase , Inosinicase, IMP synthetase
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:P31939 ATIC
Gene Names
ATIC, PURH, OK/SW-cl.86
Chain
chain:1-592, initiator methionine:, chain:2-592
Reference Genes
BioGPS Gene:471 ATIC
COSMIC (genes):ATIC ATIC
CTD Gene:471 ATIC
dbSNP Gene:471 ATIC
ENSEMBL:ENSG00000138363 ATIC
HGNC:794 ATIC
KEGG:hsa:471 ATIC
Monarch:471 ATIC
NCBI Gene:471 ATIC
OMIM:601731 ATIC
UCSC:P31939 ATIC
Reference Transcript
Other Identifiers
11715755_a_at
16890490
208758_PM_at
208758_at
2526766
2526767
2526768
2526769
2526770
2526771
2526772
2526776
2526777
2526778
2526779
2526780
2526781
2526782
2526783
2526784
2526785
2526786
2526787
2526788
2526793
2526794
2526795
2526796
2526797
2526798
2526799
2526800
2526801
2526802
2526803
2526804
2526805
3771131
38811_at
471
76913_at
8048120
A_14_P101313
A_14_P117158
A_23_P68087
D82348_at
GE57324
GO:0003360
GO:0003824
GO:0003937
GO:0004643
GO:0005737
GO:0005829
GO:0005886
GO:0006139
GO:0006164
GO:0006177
GO:0006189
GO:0006575
GO:0016020
GO:0016740
GO:0016787
GO:0021549
GO:0021987
GO:0031100
GO:0042803
GO:0043226
GO:0044208
GO:0045296
GO:0046452
GO:0046654
GO:0048856
GO:0055086
GO:0070062
GO:0097294
GO:0098761
GO:1901135
HMNXSV003041780
ILMN_1673991
PH_hs_0005040
TC02001260.hg
TC02003807.hg
g2317691_3p_at
Participates
as a component of
Other forms of this molecule
ATIC(1-230)-p-7Y-ALK(1059-1620) fusion [cytosol]
ATIC(1-229)-p-7Y-ALK(1058-1620) fusion [cytosol]
ATIC(1-230)-ALK(1059-1620) fusion [cytosol]
ATIC(1-229)-ALK(1058-1620) fusion [cytosol]
Inferred To
PURH [cytosol] (Gallus gallus)
BEST:GH11240 [cytosol] (Drosophila melanogaster)
atic [cytosol] (Danio rerio)
atic-1 [cytosol] (Caenorhabditis elegans)
ATIC [cytosol] (Bos taurus)
ATIC [cytosol] (Canis familiaris)
ATIC [cytosol] (Dictyostelium discoideum)
ATIC [cytosol] (Mus musculus)
ATIC [cytosol] (Rattus norvegicus)
ATIC [cytosol] (Saccharomyces cerevisiae)
ATIC [cytosol] (Schizosaccharomyces pombe)
ATIC [cytosol] (Sus scrofa)
Cross References
ENSEMBL
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Metabolites
IntEnz
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (1)
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