PIP2 hydrolysis

Stable Identifier
R-HSA-622382
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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PIP2 hydrolysis appers to be an important mechanism for netrin-1 mediated neurite elongation. Netrin-1 alone could not elicit hydrolysis of PIP2 but depends on the stimulation of DCC and PLCgamma.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
phosphatidylinositol phospholipase C activity of p-4Y-PLCG1 [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created
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