Reactome | AGAP2 [cytosol]

AGAP2 [cytosol]

Stable Identifier

R-HSA-622355

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PIKE-L, Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2, AGAP2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99490 AGAP2

Gene Names

AGAP2, CENTG1, KIAA0167

Chain

chain:1-1192

Reference Genes

BioGPS Gene:116986 AGAP2

COSMIC (genes):AGAP2 AGAP2

CTD Gene:116986 AGAP2

dbSNP Gene:116986 AGAP2

ENSEMBL:ENSG00000135439 AGAP2

HGNC:16921 AGAP2

KEGG:hsa:116986 AGAP2

Monarch:116986 AGAP2

NCBI Gene:116986 AGAP2

OMIM:605476 AGAP2

UCSC:Q99490 AGAP2

Reference Transcript

Participates

as a component of

UNC5B:AGAP2 [plasma membrane] (Homo sapiens)

as an input of

PIKE-L interaction with UNC5B (Homo sapiens)

Cross References

RefSeq

NP_001116244.1, NP_055585.1

ENSEMBL

ENST00000257897, ENSG00000135439, ENSP00000257897

OpenTargets

ENSG00000135439

GeneCards

AGAP2

HPA

ENSG00000135439-AGAP2

PRO

Q99490

Pharos - Targets

Q99490

GlyGen

Q99490

HMDB Protein

HMDBP01603

PDB

2RLO, 2IWR, 2BMJ

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06213 INSR	6	INSR(28-758) [plasma membrane] (R-HSA-74668) p-6Y-INSR(763-1382) [plasma membrane] (R-HSA-74670) INSR(763-1382) [plasma membrane] (R-HSA-74669) INSR(28-758) [endosome membrane] (R-HSA-141718) INSR(763-1382) [endosome membrane] (R-HSA-141722) p-6Y-INSR(763-1382) [endosome membrane] (R-HSA-141719)	0.524	2

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