Reactome | TRPC4 [plasma membrane]

TRPC4 [plasma membrane]

Stable Identifier

R-HSA-612169

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Short transient receptor potential channel 4, TRPC4_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Nervous system development (Homo sapiens)
  - Axon guidance (Homo sapiens)
    - Netrin-1 signaling (Homo sapiens)
      - Role of second messengers in netrin-1 signaling (Homo sapiens)
        
        Activation of TRPC channels by Netrin-1 (Homo sapiens)
        
        Activated TRP channels [plasma membrane] (Homo sapiens)
        
        TRPC1+4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4 [plasma membrane] (Homo sapiens)
        
        TRPC channels [plasma membrane] (Homo sapiens)
        
        TRPC1+4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4/5 [plasma membrane] (Homo sapiens)
        
        TRPC4 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UBN4 TRPC4

Gene Names

TRPC4

Chain

chain:1-977

Reference Genes

BioGPS Gene:7223 TRPC4

COSMIC (genes):TRPC4 TRPC4

CTD Gene:7223 TRPC4

dbSNP Gene:7223 TRPC4

ENSEMBL:ENSG00000133107 TRPC4

ENSEMBL_homo_sapiens_GENE:ENSG00000133107.15 TRPC4

HGNC:12336 TRPC4

KEGG Gene (Homo sapiens):7223 TRPC4

Monarch:7223 TRPC4

NCBI Gene:7223 TRPC4

OMIM:603651 TRPC4

UCSC:Q9UBN4 TRPC4

Reference Transcript

Other Identifiers

11733319_a_at

16778274

220817_PM_at

220817_at

220818_PM_s_at

220818_s_at

224219_PM_s_at

224219_s_at

224220_PM_x_at

224220_x_at

3510121

3510123

3510125

3510127

3510128

3510129

3510130

3510131

3510132

3510133

3510136

3510137

3510138

3510139

3510140

3510143

3510144

3510151

3510152

3510153

3510154

3510163

3510167

3510168

3510176

3510177

3510178

3510179

54701_at

7223

78651_at

7971104

A_23_P105873

GE474264

GE772661

GE79429

GO:0005215

GO:0005216

GO:0005262

GO:0005515

GO:0005856

GO:0005886

GO:0005901

GO:0005911

GO:0006811

GO:0006816

GO:0008013

GO:0009986

GO:0014051

GO:0015279

GO:0016020

GO:0016323

GO:0030154

GO:0030863

GO:0032991

GO:0034220

GO:0034703

GO:0034704

GO:0043226

GO:0045121

GO:0045296

GO:0048709

GO:0048856

GO:0051480

GO:0055065

GO:0055085

GO:0070509

GO:0070588

GO:0070679

HMNXSV003020748

ILMN_1782295

PH_hs_0013643

TC13000577.hg

g6665593_3p_a_at

g7706746_3p_x_at

Participates

as a member of

Inferred To

TRPC4 [plasma membrane] (Bos taurus)

TRPC4 [plasma membrane] (Canis familiaris)

TRPC4 [plasma membrane] (Gallus gallus)

TRPC4 [plasma membrane] (Sus scrofa)

trp-2 [plasma membrane] (Caenorhabditis elegans)

Trpc4 [plasma membrane] (Mus musculus)

Trpc4 [plasma membrane] (Rattus norvegicus)

trpc4 [plasma membrane] (Xenopus tropicalis)

Trpgamma [plasma membrane] (Drosophila melanogaster)

trpc4b [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_001129428.1, NP_001129430.1, NP_057263.1, NP_001129429.1, NP_001129427.1, NP_003297.1

Guide to Pharmacology - Targets

489

OpenTargets

ENSG00000133107

HPA

ENSG00000133107-TRPC4

GeneCards

Q9UBN4

Ensembl

ENST00000625583, ENSP00000342580, ENST00000379673, ENST00000355779, ENSP00000486109, ENST00000488717, ENSP00000369001, ENSP00000348025, ENSP00000351264, ENSP00000369027, ENSP00000368995, ENST00000379679, ENSG00000133107, ENST00000379705, ENST00000358477, ENSP00000435969, ENST00000338947

PRO

Q9UBN4

Pharos - Targets

Q9UBN4

HMDB Protein

HMDBP08076