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NMT1 [cytosol]
Stable Identifier
R-HSA-60306
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Glycylpeptide N-tetradecanoyltransferase 1 , Peptide N- myristoyltransferase 1, Myristoyl-CoA:protein N-myristoyltransferase 1, Type I N-myristoyltransferase
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Late Phase of HIV Life Cycle (Homo sapiens)
Myristoylation of Nef (Homo sapiens)
NMT1 [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Intrinsic Pathway for Apoptosis (Homo sapiens)
Activation, myristolyation of BID and translocation to mitochondria (Homo sapiens)
Myristoylation of tBID by NMT1 (Homo sapiens)
NMT1 [cytosol] (Homo sapiens)
Sensory Perception (Homo sapiens)
Visual phototransduction (Homo sapiens)
The phototransduction cascade (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
NMT1/2 transfer MYS to GNAT1 (Homo sapiens)
NMT1/2 [cytosol] (Homo sapiens)
NMT1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30419 NMT1
Gene Names
NMT1, NMT
Chain
chain:1-496
Reference Genes
BioGPS Gene:4836 NMT1
COSMIC (genes):NMT1 NMT1
CTD Gene:4836 NMT1
dbSNP Gene:4836 NMT1
ENSEMBL:ENSG00000136448 NMT1
HGNC:7857 NMT1
KEGG Gene (Homo sapiens):4836 NMT1
Monarch:4836 NMT1
NCBI Gene:4836 NMT1
OMIM:160993 NMT1
UCSC:P30419 NMT1
Reference Transcript
RefSeq:NM_021079.4 NMT1
Other Identifiers
0000380121
11722195_s_at
11722196_x_at
11722197_at
11751589_a_at
16834883
201157_PM_s_at
201157_s_at
201158_PM_at
201158_at
201159_PM_s_at
201159_s_at
3723265
3723268
3723269
3723270
3723281
3723285
3723287
3723288
3723289
3723290
3723291
3723297
3723298
3723300
3723302
3723303
3723304
3723305
3723306
3723307
3723312
3723314
38999_s_at
39000_at
8007715
A_14_P103416
A_14_P117222
A_23_P107373
A_24_P14010
GE54377
GO:0001701
GO:0003674
GO:0004379
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005829
GO:0005886
GO:0006464
GO:0006499
GO:0006810
GO:0007005
GO:0007165
GO:0008150
GO:0008219
GO:0009058
GO:0009790
GO:0015031
GO:0016020
GO:0016740
GO:0016746
GO:0018008
GO:0019107
GO:0019898
GO:0022400
GO:0042180
GO:0043226
GO:0044281
GO:0048856
GO:0061024
GO:1900740
HMNXSV003030620
HMNXSV003048730
Hs.111039.0.A1_3p_a_at
ILMN_1762678
M86707_at
PH_hs_0023902
TC17000577.hg
U79285_at
g10835072_3p_a_at
Participates
as a member of
NMT1/2 [cytosol] (Homo sapiens)
Inferred To
Nmt [cytosol]
(Drosophila melanogaster)
nmt1 [cytosol]
(Schizosaccharomyces pombe)
nmt1 [cytosol]
(Xenopus tropicalis)
nmt [cytosol]
(Dictyostelium discoideum)
nmt-1 [cytosol]
(Caenorhabditis elegans)
nmt1a [cytosol]
(Danio rerio)
Nmt1 [cytosol]
(Mus musculus)
Nmt1 [cytosol]
(Rattus norvegicus)
NMT1 [cytosol]
(Bos taurus)
NMT1 [cytosol]
(Canis familiaris)
NMT1 [cytosol]
(Gallus gallus)
NMT1 [cytosol]
(Saccharomyces cerevisiae)
NMT1 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_066565.1
OpenTargets
ENSG00000136448
ZINC - Substances
NMT1_HUMAN
ZINC target
P30419
PRO
P30419
PDB
3IU2
,
6EHJ
,
5O9S
,
6SKJ
,
6FZ5
,
3JTK
,
5UUT
,
6QRM
,
5MU6
,
6FZ3
,
5NPQ
,
3IU1
,
1RXT
,
6PAV
,
5O6J
,
6FZ2
,
6F56
,
4C2Z
,
6SK8
,
6SJZ
,
6SK2
,
5O9T
,
5O6H
,
6SK3
,
4C2Y
,
5O9U
,
3IWE
,
5O9V
ZINC - Investigational
NMT1_HUMAN
HPA
ENSG00000136448-NMT1
GeneCards
P30419
Ensembl
ENST00000676828
,
ENSP00000503621
,
ENSP00000466827
,
ENST00000678938
,
ENST00000258960
,
ENSG00000136448
,
ENST00000592782
,
ENST00000592654
,
ENSP00000468424
,
ENSP00000258960
,
ENSP00000504192
Pharos - Targets
P30419
ZINC - Predictions - Purchasable
NMT1_HUMAN
HMDB Protein
HMDBP01578
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BR61 ACBD6
1
ACBD6 [cytosol]
(R-HSA-8848243)
0.697
5
UniProt:P04601 nef
3
nef [cytosol]
(R-HIV-165575)
myristoylated nef [cytosol]
(R-HIV-167605)
myristoylated Nef Protein (UniProt:P04601) [extracellular region]
(R-HIV-3597665)
0.462
4
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