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Go!
USP49 [nucleoplasm]
Stable Identifier
R-HSA-5696973
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin carboxyl-terminal hydrolase 49 ecNumber3.4.19.12/ecNumber, UBP49_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP49 deubiquitinates H2B (Homo sapiens)
USP49 [nucleoplasm] (Homo sapiens)
USP49:Histone H2B [nucleoplasm] (Homo sapiens)
USP49 [nucleoplasm] (Homo sapiens)
USP49:Ub-histone H2B [nucleoplasm] (Homo sapiens)
USP49 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q70CQ1 USP49
Gene Names
USP49
Chain
chain:1-688
Reference Genes
BioGPS Gene:25862 USP49
COSMIC (genes):USP49 USP49
CTD Gene:25862 USP49
dbSNP Gene:25862 USP49
ENSEMBL:ENSG00000164663 USP49
ENSEMBL_homo_sapiens_GENE:ENSG00000164663.15 USP49
HGNC:20078 USP49
KEGG Gene (Homo sapiens):25862 USP49
Monarch:25862 USP49
NCBI Gene:25862 USP49
UCSC:Q70CQ1 USP49
Reference Transcript
RefSeq:NM_018561.4 USP49
RefSeq:NM_001286554.1 USP49
Other Identifiers
11737273_at
17019134
229351_PM_at
229351_at
242120_PM_at
242120_at
243392_PM_at
243392_at
244133_PM_at
244133_at
25862
2953793
2953795
2953796
2953797
2953799
2953800
2953801
2953802
2953803
2953804
2953805
2953806
2953807
2953808
2953809
2953810
2953811
2953812
2953813
2953814
2953815
2953819
2953820
2953821
2953822
2953823
2953824
2953825
2953826
2953836
2953842
2953844
2953845
2953846
44172_at
76141_at
8126347
82600_at
A_23_P331770
A_24_P166473
A_33_P3389967
A_33_P3389973
GE56444
GE572169
GE828433
GO:0000398
GO:0003824
GO:0004197
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006325
GO:0006338
GO:0006397
GO:0006508
GO:0006807
GO:0008233
GO:0008234
GO:0008270
GO:0008380
GO:0016071
GO:0016579
GO:0016787
GO:0036211
GO:0042393
GO:0043170
GO:0043226
GO:0044238
GO:0046872
GO:0140096
GO:0140936
HMNXSV003014058
Hs.116808.0.A1_3p_at
Hs.144049.0.A1_3p_at
Hs.269254.0.A1_3p_at
Hs.293179.0.A1_3p_at
ILMN_1680279
PH_hs_0026582
TC06001724.hg
TC06001725.hg
TC06003647.hg
p26333
Participates
as a component of
USP49:Histone H2B [nucleoplasm] (Homo sapiens)
USP49:Ub-histone H2B [nucleoplasm] (Homo sapiens)
Inferred To
usp49 [nucleoplasm]
(Danio rerio)
usp49 [nucleoplasm]
(Xenopus tropicalis)
USP49 [nucleoplasm]
(Bos taurus)
USP49 [nucleoplasm]
(Canis familiaris)
USP49 [nucleoplasm]
(Dictyostelium discoideum)
USP49 [nucleoplasm]
(Gallus gallus)
USP49 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_061031.2
,
NP_001273483.1
OpenTargets
ENSG00000164663
IntEnz
3.4.19.12
HPA
ENSG00000164663-USP49
GeneCards
Q70CQ1
Ensembl
ENST00000682992
,
ENST00000373006
,
ENSP00000507239
,
ENSG00000164663
,
ENSP00000362097
,
ENSP00000377797
,
ENST00000394253
PRO
Q70CQ1
Pharos - Targets
Q70CQ1
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13451 FKBP5
2
FKBP5 [cytosol]
(R-HSA-5618096)
FKBP5 [nucleoplasm]
(R-HSA-8939165)
0.589
2
UniProt:P41208 CETN2
3
CETN2 [cytosol]
(R-HSA-380298)
CETN2 [nucleoplasm]
(R-HSA-4570490)
polySUMO2,3-CETN2 [nucleoplasm]
(R-HSA-4570486)
0.564
2
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