Reactome | WDR20 [nucleoplasm]

WDR20 [nucleoplasm]

Stable Identifier

R-HSA-5696932

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

WD repeat-containing protein 20, WDR20_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP12, USP26 deubiquitinate AR (Homo sapiens)
        
        USP12:WDR48:WDR20,USP26 [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20 [nucleoplasm] (Homo sapiens)
        
        WDR20 [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20,USP26:AR [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20,USP26 [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20 [nucleoplasm] (Homo sapiens)
        
        WDR20 [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20,USP26:PolyUb-AR [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20,USP26 [nucleoplasm] (Homo sapiens)
        
        USP12:WDR48:WDR20 [nucleoplasm] (Homo sapiens)
        
        WDR20 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8TBZ3 WDR20

Gene Names

WDR20

Chain

initiator methionine:1, chain:2-569

Reference Genes

BioGPS Gene:91833 WDR20

COSMIC (genes):WDR20 WDR20

CTD Gene:91833 WDR20

dbSNP Gene:91833 WDR20

ENSEMBL:ENSG00000140153 WDR20

ENSEMBL:ENSG00000140153.18 WDR20

HGNC:19667 WDR20

KEGG Gene (Homo sapiens):91833 WDR20

Monarch:91833 WDR20

NCBI Gene:91833 WDR20

OMIM:617741 WDR20

UCSC:Q8TBZ3 WDR20

Reference Transcript

Other Identifiers

11723486_a_at

11725500_s_at

11747992_a_at

11760388_a_at

1554549_3p_a_at

1554549_PM_a_at

1554549_a_at

227541_PM_at

227541_at

227693_PM_at

227693_at

3553018

3553019

3553020

3553021

3553022

3553043

3553044

3553048

3553058

3553059

3553060

3553061

3553062

3553063

3553064

3553065

3553066

3553067

3553068

3553069

3553070

3553071

3553072

3553073

3553074

3553075

3553079

3553080

3553081

3553082

46100_at

53157_at

7976957

83063_at

91833

A_14_P116780

A_23_P205255

A_24_P162412

A_24_P184769

A_33_P3235009

GE56619

GO:0005515

GO:0005634

GO:0005654

GO:0043226

HMNXSV003010942

HMNXSV003031765

HMNXSV003032689

HMNXSV003033100

HMNXSV003041917

Hs.55209.0.S1_3p_at

Hs.57637.0.A1_3p_at

Hs2.283304.1.S1_3p_at

Hs2.283304.1.S1_3p_s_at

ILMN_1707199

ILMN_2361324

ILMN_2409706

PH_hs_0003623

TC14001876.hg

p33774

Participates

as a component of

USP12:WDR48:WDR20 [nucleoplasm] (Homo sapiens)

Inferred To

WDR20 [nucleoplasm] (Bos taurus)

WDR20 [nucleoplasm] (Canis familiaris)

WDR20 [nucleoplasm] (Danio rerio)

WDR20 [nucleoplasm] (Dictyostelium discoideum)

WDR20 [nucleoplasm] (Gallus gallus)

WDR20 [nucleoplasm] (Sus scrofa)

bun62 [nucleoplasm] (Schizosaccharomyces pombe)

Dmel\CG6420 [nucleoplasm] (Drosophila melanogaster)

Wdr20 [nucleoplasm] (Mus musculus)

Wdr20 [nucleoplasm] (Rattus norvegicus)

wdr-20 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001229344.1, NP_851808.1, NP_001229343.1, NP_001229347.1, NP_653175.2, NP_001229345.1, NP_001229346.1, NP_851825.1

OpenTargets

ENSG00000140153

HPA

ENSG00000140153-WDR20

GeneCards

Q8TBZ3

Ensembl

ENST00000454394, ENST00000322340, ENST00000556807, ENST00000555879, ENSP00000452470, ENSP00000451633, ENSG00000140153, ENST00000299135, ENSP00000450636, ENST00000342702, ENST00000556511, ENSP00000341037, ENSP00000335434, ENST00000335263, ENSP00000314209, ENSP00000406084, ENSP00000299135

PRO

Q8TBZ3

Pharos - Targets

Q8TBZ3

PDB

5K1C, 5K19, 6JLQ

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UN19 DAPP1	2	p-Y139-DAPP1 [plasma membrane] (R-HSA-1112650) DAPP1 [cytosol] (R-HSA-197950)	0.57	3
UniProt:Q8TAF3 WDR48	3	p-12Y-WDR48(1-323)-PDGFRB(559-1106) fusion [cytosol] (R-HSA-9673645) WDR48(1-323)-PDGFRB(559-1106) fusion [cytosol] (R-HSA-9673617) WDR48 [nucleoplasm] (R-HSA-419549)	0.564	3