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RPP40 [nucleoplasm]
Stable Identifier
R-HSA-5696801
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ribonuclease P protein subunit p40, RPP40_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
Major pathway of rRNA processing in the nucleolus and cytosol (Homo sapiens)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Homo sapiens)
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RPP40 [nucleoplasm] (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA processing in the nucleus (Homo sapiens)
RNase P cleaves the 5' end of pre-tRNA (Homo sapiens)
RNase P [nucleoplasm] (Homo sapiens)
RPP40 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75818 RPP40
Gene Names
RPP40, RNASEP1
Chain
chain:1-363
Reference Genes
BioGPS Gene:10799 RPP40
COSMIC (genes):RPP40 RPP40
CTD Gene:10799 RPP40
dbSNP Gene:10799 RPP40
ENSEMBL:ENSG00000124787 RPP40
HGNC:20992 RPP40
Monarch:10799 RPP40
NCBI Gene:10799 RPP40
OMIM:606117 RPP40
UCSC:O75818 RPP40
Reference Transcript
RefSeq:NM_006638.3 RPP40
RefSeq:NM_001286132.1 RPP40
RefSeq:NM_001286133.1 RPP40
Other Identifiers
10799
11724083_a_at
17015277
213427_PM_at
213427_at
2939829
2939830
2939832
2939834
2939835
2939837
2939838
2939839
2939840
2939841
2939842
2939843
37471_at
8123717
A_23_P111297
GE59581
GO:0000171
GO:0000172
GO:0000447
GO:0001682
GO:0003723
GO:0003824
GO:0004526
GO:0005515
GO:0005634
GO:0005654
GO:0005655
GO:0005730
GO:0006364
GO:0006399
GO:0008033
GO:0016787
GO:0030677
GO:0030681
GO:0033204
GO:0043226
GO:0140098
HMNXSV003020615
Hs.115823.0.S1_3p_at
ILMN_1810423
PH_hs_0026611
TC06001239.hg
Participates
as a component of
18SE pre-40S particle [nucleoplasm] (Homo sapiens)
RNase P [nucleoplasm] (Homo sapiens)
Inferred To
Rpp40 [nucleoplasm]
(Mus musculus)
Rpp40 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of RPP40 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of RPP40 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of RPP40 [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of RPP40 [nucleoplasm]
(Saccharomyces cerevisiae)
RPP40 [nucleoplasm]
(Bos taurus)
RPP40 [nucleoplasm]
(Canis familiaris)
RPP40 [nucleoplasm]
(Gallus gallus)
RPP40 [nucleoplasm]
(Schizosaccharomyces pombe)
RPP40 [nucleoplasm]
(Sus scrofa)
drpp40 [nucleoplasm]
(Dictyostelium discoideum)
rpp40 [nucleoplasm]
(Danio rerio)
rpp40 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000319533
,
ENSP00000317998
,
ENSP00000369391
,
ENST00000380051
OpenTargets
ENSG00000124787
HPA
ENSG00000124787-RPP40
PRO
O75818
Pharos - Targets
O75818
PDB
6AHR
,
6AHV
,
6AHU
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.527
3
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