Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TSEN2 [nucleoplasm]
Stable Identifier
R-HSA-5696787
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
tRNA-splicing endonuclease subunit Sen2 ecNumber4.6.1.16/ecNumber, SEN2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA processing in the nucleus (Homo sapiens)
TSEN complex cleaves the intron from pre-tRNA (Homo sapiens)
TSEN complex [nucleoplasm] (Homo sapiens)
TSEN2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8NCE0 TSEN2
Gene Names
TSEN2, SEN2
Chain
chain:1-465
Reference Genes
BioGPS Gene:80746 TSEN2
COSMIC (genes):TSEN2 TSEN2
CTD Gene:80746 TSEN2
dbSNP Gene:80746 TSEN2
ENSEMBL:ENSG00000154743 TSEN2
HGNC:28422 TSEN2
Monarch:80746 TSEN2
NCBI Gene:80746 TSEN2
OMIM:608753 TSEN2
UCSC:Q8NCE0 TSEN2
Reference Transcript
RefSeq:NM_001321277.1 TSEN2
RefSeq:NM_001145392.1 TSEN2
RefSeq:NM_001145393.2 TSEN2
RefSeq:NM_025265.3 TSEN2
RefSeq:NM_001321278.1 TSEN2
RefSeq:NM_001321279.1 TSEN2
RefSeq:NM_001145394.1 TSEN2
RefSeq:XM_017007296.1 TSEN2
Other Identifiers
11740281_at
11740282_a_at
11742936_a_at
16937766
219581_PM_at
219581_at
244391_PM_at
244391_at
2611128
2611129
2611130
2611131
2611132
2611133
2611134
2611137
2611138
2611139
2611141
2611144
2611147
2611148
2611149
2611150
2611151
2611152
2611153
2611154
2611155
2611156
2611162
2611163
2611164
2611168
2611170
2611171
2611172
2611173
2611174
2611175
2611176
2611177
2611178
2611179
2611180
2611181
2611182
2611183
2611184
2611186
2611187
2611188
2611189
2611190
2611191
2611192
2611201
2611205
2752408
47908_at
80746
8077914
A_14_P115328
A_23_P92012
A_32_P53538
A_33_P3350913
GE83146
GE85306
GO:0000213
GO:0000214
GO:0000379
GO:0003676
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005813
GO:0005815
GO:0005829
GO:0006388
GO:0006397
GO:0006399
GO:0008033
GO:0016071
GO:0016787
GO:0016829
GO:0043226
GO:0140098
HMNXSV003007939
HMNXSV003025297
HMNXSV003030254
HMNXSV003035600
HMNXSV003054025
ILMN_1746393
PH_hs_0023872
TC03000070.hg
TC03002225.hg
g13376881_3p_at
g13376881_3p_x_at
p26806
Participates
as a component of
TSEN complex [nucleoplasm] (Homo sapiens)
Cross References
OpenTargets
ENSG00000154743
ENSEMBL
ENST00000679699
,
ENST00000681471
,
ENST00000681676
,
ENSP00000385976
,
ENST00000284995
,
ENST00000679670
,
ENST00000679756
,
ENSP00000505442
,
ENSP00000506391
,
ENSP00000505105
,
ENSP00000506297
,
ENSP00000506080
,
ENST00000681140
,
ENST00000415684
,
ENST00000680598
,
ENST00000681482
,
ENSP00000392029
,
ENST00000402228
,
ENSP00000284995
,
ENSP00000416510
,
ENST00000679425
,
ENSP00000505099
,
ENST00000454502
,
ENSP00000505890
,
ENST00000680943
,
ENSP00000505436
,
ENSP00000506163
,
ENSP00000505274
,
ENSP00000505799
,
ENST00000680986
HPA
ENSG00000154743-TSEN2
PRO
Q8NCE0
Pharos - Targets
Q8NCE0
Orphanet
TSEN2
GlyGen
Q8NCE0
PDB
8ISS
,
7UXA
,
7ZRZ
,
8HMY
,
8HMZ
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text