ADPRM hydrolyses ADP-ribose to R5P and AMP

Stable Identifier
R-HSA-5696049
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase (ADPRM:Mn2+) can mediate the hydrolysis of ADP-ribose and less efficiently, CDP-alcohols and 2',3'-cAMP (Cabezas et al. 2015).

Literature References
PubMed ID Title Journal Year
25692488 Molecular bases of catalysis and ADP-ribose preference of human Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase and conversion by mutagenesis to a preferential cyclic ADP-ribose phosphohydrolase

Cabezas, A, Ribeiro, JM, Rodrigues, JR, López-Villamizar, I, Fernández, A, Canales, J, Pinto, RM, Costas, MJ, Cameselle, JC

PLoS ONE 2015
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ADP-ribose diphosphatase activity of ADPRM:Mn2+ [cytosol]
Physical Entity
Activity
Orthologous Events
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Reviewed
Created