Reactome | AGK [mitochondrial outer membrane]

AGK [mitochondrial outer membrane]

Stable Identifier

R-HSA-5696027

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Acylglycerol kinase, mitochondrial, AGK_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q53H12 AGK

Gene Names

AGK, MULK

Chain

chain:1-422

Reference Genes

COSMIC (genes):AGK Q53H122

dbSNP Gene:55750 Q53H122

ENSEMBL:ENSG00000006530 AGK

ENSEMBL:ENSG00000262327 AGK

Participates

as a component of

AGK:Mg2+ [mitochondrial outer membrane] (Homo sapiens)

Other forms of this molecule

AGK(1-33)InsW-BRAF(328-766) fusion [cytosol]

AGK(1-33)InsW-p-BRAF(328-766) fusion [cytosol]

Inferred To

Homologues of AGK [mitochondrial outer membrane] (Dictyostelium discoideum)

Homologues of AGK [mitochondrial outer membrane] (Saccharomyces cerevisiae)

Homologues of AGK [mitochondrial outer membrane] (Schizosaccharomyces pombe)

tim54 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

agk [mitochondrial outer membrane] (Danio rerio)

agk [mitochondrial outer membrane] (Xenopus tropicalis)

Mulk [mitochondrial outer membrane] (Drosophila melanogaster)

Agk [mitochondrial outer membrane] (Mus musculus)

Agk [mitochondrial outer membrane] (Rattus norvegicus)

TIM54 [mitochondrial outer membrane] (Saccharomyces cerevisiae)

AGK [mitochondrial outer membrane] (Bos taurus)

AGK [mitochondrial outer membrane] (Caenorhabditis elegans)

AGK [mitochondrial outer membrane] (Canis familiaris)

AGK [mitochondrial outer membrane] (Dictyostelium discoideum)

AGK [mitochondrial outer membrane] (Gallus gallus)

AGK [mitochondrial outer membrane] (Saccharomyces cerevisiae)

AGK [mitochondrial outer membrane] (Schizosaccharomyces pombe)

AGK [mitochondrial outer membrane] (Sus scrofa)

sgkC [mitochondrial outer membrane] (Dictyostelium discoideum)

sgkD [mitochondrial outer membrane] (Dictyostelium discoideum)

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53701 HCCS	1	HCCS [mitochondrial inner membrane] (R-HSA-9866218)	0.623	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9Y5J6 TIMM10B	1	4xHC-TIMM10B [mitochondrial inner membrane] (R-HSA-1252043)	0.527	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	8

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