Reactome | AGK [mitochondrial outer membrane]

AGK [mitochondrial outer membrane]

Stable Identifier

R-HSA-5696027

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Acylglycerol kinase, mitochondrial, AGK_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q53H12 AGK

Gene Names

AGK, MULK

Chain

chain:1-422

Reference Genes

BioGPS Gene:55750 Q53H122

COSMIC (genes):AGK AGK

CTD Gene:55750 Q53H122

dbSNP Gene:55750 AGK

ENSEMBL:ENSG00000006530 AGK

ENSEMBL:ENSG00000262327 AGK

HGNC:21869 Q53H122

KEGG:hsa:55750 Q53H122

Monarch:55750 Q53H122

NCBI Gene:55750 Q53H122

OMIM:610345 Q53H122

UCSC:Q53H12 Q53H122

Reference Transcript

Participates

as a component of

AGK:Mg2+ [mitochondrial outer membrane] (Homo sapiens)

Other forms of this molecule

AGK(1-33)InsW-p-BRAF(328-766) fusion [cytosol]

AGK(1-33)InsW-BRAF(328-766) fusion [cytosol]

Inferred To

LCB5 [mitochondrial outer membrane] (Saccharomyces cerevisiae)

agk [mitochondrial outer membrane] (Danio rerio)

agk [mitochondrial outer membrane] (Xenopus tropicalis)

Mulk [mitochondrial outer membrane] (Drosophila melanogaster)

Agk [mitochondrial outer membrane] (Mus musculus)

Agk [mitochondrial outer membrane] (Rattus norvegicus)

AGK [mitochondrial outer membrane] (Bos taurus)

AGK [mitochondrial outer membrane] (Caenorhabditis elegans)

AGK [mitochondrial outer membrane] (Canis familiaris)

AGK [mitochondrial outer membrane] (Gallus gallus)

AGK [mitochondrial outer membrane] (Sus scrofa)

lcb4 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

sgkA [mitochondrial outer membrane] (Dictyostelium discoideum)

Cross References

RefSeq

XP_024302603.1, XP_054214619.1, XP_054214618.1, XP_011514699.1, NP_060708.1

OpenTargets

ENSG00000006530

ENSEMBL

ENST00000575872, ENST00000650547, ENSP00000498112, ENSP00000418789, ENSP00000458417, ENSG00000006530, ENSP00000497280, ENST00000492693, ENSP00000496789, ENST00000649286, ENSG00000262327, ENST00000648068

HPA

ENSG00000006530-AGK

GeneCards

AGK

PRO

Q53H12

Pharos - Targets

Q53H12

Orphanet

AGK

PDB

7CGP

HMDB Protein

HMDBP08704

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53701 HCCS	1	HCCS [mitochondrial inner membrane] (R-HSA-9866218)	0.623	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9Y5J6 TIMM10B	1	4xHC-TIMM10B [mitochondrial inner membrane] (R-HSA-1252043)	0.527	4
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279)	0.483	8

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