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ACSF3 [mitochondrial matrix]
Stable Identifier
R-HSA-5696011
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Acyl-CoA synthetase family member 3, mitochondrial ecNumber6.2.1.-/ecNumber, ACSF3_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q96KQ4 PPP1R13B
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
ACSF3 ligates CoA-SH to VLCFA (Homo sapiens)
ACSF3 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q4G176 ACSF3
Gene Names
ACSF3, PSEC0197
Chain
transit peptide:1-83, chain:84-576
Reference Genes
BioGPS Gene:197322 ACSF3
COSMIC (genes):ACSF3 ACSF3
CTD Gene:197322 ACSF3
dbSNP Gene:197322 ACSF3
ENSEMBL:ENSG00000176715 ACSF3
ENSEMBL_homo_sapiens_GENE:ENSG00000176715.17 ACSF3
HGNC:27288 ACSF3
KEGG Gene (Homo sapiens):197322 ACSF3
Monarch:197322 ACSF3
NCBI Gene:197322 ACSF3
OMIM:614245 ACSF3
UCSC:Q4G176 ACSF3
Reference Transcript
RefSeq:NM_001243279.2 ACSF3
RefSeq:NM_174917.4 ACSF3
RefSeq:NM_001127214.3 ACSF3
Other Identifiers
11734838_a_at
11754897_a_at
1556552_PM_a_at
1556552_a_at
16821894
197322
227464_PM_at
227464_at
3673824
3673828
3673829
3673830
3673833
3673836
3673840
3673841
3673844
3673846
3673857
3673858
3673859
3673869
3673870
3673871
57597_at
7997863
A_14_P136006
A_32_P218332
GE87809
GO:0000166
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005739
GO:0005759
GO:0006629
GO:0006631
GO:0006633
GO:0006790
GO:0016874
GO:0016878
GO:0031957
GO:0035338
GO:0043226
GO:0055086
GO:0090409
GO:0090410
GO:0140657
GO:1901135
HMNXSV003040375
Hs2.123661.1.S1_3p_a_at
ILMN_1716832
PH_hs_0025382
TC16000689.hg
TC16001704.hg
Inferred To
ACSF3 [mitochondrial matrix]
(Bos taurus)
ACSF3 [mitochondrial matrix]
(Dictyostelium discoideum)
ACSF3 [mitochondrial matrix]
(Mus musculus)
ACSF3 [mitochondrial matrix]
(Sus scrofa)
Acsf3 [mitochondrial matrix]
(Drosophila melanogaster)
Acsf3 [mitochondrial matrix]
(Rattus norvegicus)
Cross References
RefSeq
NP_777577.2
,
NP_001120686.1
,
NP_001230208.1
OpenTargets
ENSG00000176715
HPA
ENSG00000176715-ACSF3
GeneCards
Q4G176
Ensembl
ENST00000406948
,
ENSG00000176715
,
ENSP00000320646
,
ENST00000317447
,
ENSP00000479130
,
ENST00000614302
,
ENSP00000384627
PRO
Q4G176
Pharos - Targets
Q4G176
Orphanet
20732
HMDB Protein
HMDBP10999
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
0.615
5
UniProt:Q9BQ13 KCD14
0.564
2
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:P51157 RAB28
0.556
3
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.556
3
UniProt:Q96KQ4 PPP1R13B
1
PPP1R13B [nucleoplasm]
(R-HSA-6799775)
0.556
3
UniProt:O95460-2 MATN4
0.556
3
UniProt:O75251 NDUFS7
1
NDUFS7 [mitochondrial matrix]
(R-HSA-6788521)
0.527
3
UniProt:Q9BVS5 TRMT61B
1
TRMT61B [mitochondrial matrix]
(R-HSA-6787512)
0.527
2
UniProt:Q6ZMB5 T184A
0.527
2
UniProt:P21912 SDHB
2
SDHB [mitochondrial matrix]
(R-HSA-9854983)
SDHB [mitochondrial inner membrane]
(R-HSA-70985)
0.527
2
UniProt:Q5BKU9 OXLD1
0.527
2
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