ACAD11 dehydrogenates BH-CoA

Stable Identifier
R-HSA-5695989
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix, mitochondrial inner membrane
ReviewStatus
5/5
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ACAD11 dehydrogenates BH-CoA
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Acyl-CoA dehydrogenase family member 11 (ACAD11) is a mitochondrial membrane-bound enzyme that can catalyse the alpha, beta-dehydrogenation of acyl-CoA esters. ACAD11 shows highest expression in the brain and is shown to dehydrogenate the C22 acyl-CoA behenoyl-CoA (BH-CoA) to 2,3-dehydrobehenoyl-CoA (DBH-CoA) (He et al. 2011).
Literature References
PubMed ID Title Journal Year
21237683 Identification and characterization of new long chain acyl-CoA dehydrogenases

Murdoch, G, Mohsen, AW, Watkins, P, Ensenauer, R, He, M, Van Veldhoven, PP, Pei, Z, Vockley, J

Mol. Genet. Metab. 2011
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as an event of
Catalyst Activity

acyl-CoA dehydrogenase activity of ACAD11 [mitochondrial inner membrane]

Physical Entity
ACAD11 [mitochondrial inner membrane] (Homo sapiens)
Activity
acyl-CoA dehydrogenase activity (GO:0003995)
Orthologous Events
ACAD11 dehydrogenates BH-CoA (Bos taurus)
ACAD11 dehydrogenates BH-CoA (Canis familiaris)
ACAD11 dehydrogenates BH-CoA (Danio rerio)
ACAD11 dehydrogenates BH-CoA (Gallus gallus)
ACAD11 dehydrogenates BH-CoA (Mus musculus)
ACAD11 dehydrogenates BH-CoA (Rattus norvegicus)
ACAD11 dehydrogenates BH-CoA (Sus scrofa)
ACAD11 dehydrogenates BH-CoA (Xenopus tropicalis)
Authored
Jassal, B  (2015-05-26)
Reviewed
D'Eustachio, P  (2015-06-26)
Created
Jassal, B  (2015-05-26)
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