Acyl-CoA dehydrogenase family member 11 (ACAD11) is a mitochondrial membrane-bound enzyme that can catalyse the alpha, beta-dehydrogenation of acyl-CoA esters. ACAD11 shows highest expression in the brain and is shown to dehydrogenate the C22 acyl-CoA behenoyl-CoA (BH-CoA) to 2,3-dehydrobehenoyl-CoA (DBH-CoA) (He et al. 2011).
Van Veldhoven, PP,
acyl-CoA dehydrogenase activity of ACAD11 [mitochondrial inner membrane]