SEC24A,B:SEC23A bind SEC22B

Stable Identifier
R-HSA-5694415
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Of the four human SEC24 isoforms, SEC24A and B are required for packaging the v-SNARE SEC22 into COPII vesicles. Recognition of the ER packaging epitope on SEC22 also depends on SEC23A (Mancias and Goldberg, 2007).

Literature References
PubMed ID Title Journal Year
17499046 The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope

Mancias, JD, Goldberg, J

Mol. Cell 2007
Participants
Participant Of
Orthologous Events
Authored
Reviewed