Reactome | protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen]

protein:(GlcNAc)2 (Man)8c

Stable Identifier

R-HSA-5694211

Type

Complex

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Locations in the PathwayBrowser

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Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        Loss of SAR1B GTPase (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        Cargo concentration in the ER (Homo sapiens)
        
        Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        LMAN family proteins bind glycosylated cargo (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
      - Loss of SAR1B GTPase (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
      - SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
      - Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
    - Cargo concentration in the ER (Homo sapiens)
      - Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
      - LMAN family proteins bind glycosylated cargo (Homo sapiens)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)
        
        glycosylated LMAN cargo [endoplasmic reticulum lumen] (Homo sapiens)
        
        Glycoproteins with Man8 N-glycans [endoplasmic reticulum lumen] (Homo sapiens)
        
        protein:(GlcNAc)2 (Man)8c [endoplasmic reticulum lumen] (Homo sapiens)