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ADORA3 [plasma membrane]
Stable Identifier
R-HSA-5693919
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Adenosine receptor A3, AA3R_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Nucleotide-like (purinergic) receptors (Homo sapiens)
Adenosine P1 receptors (Homo sapiens)
A1 and A3 receptors bind adenosine (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
ADORA1,3:Ade-Rib [plasma membrane] (Homo sapiens)
ADORA1,3 [plasma membrane] (Homo sapiens)
ADORA3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P0DMS8 ADORA3
Gene Names
ADORA3
Chain
chain:1-318
Reference Genes
BioGPS Gene:140 ADORA3
COSMIC (genes):ADORA3 ADORA3
CTD Gene:140 ADORA3
dbSNP Gene:140 ADORA3
ENSEMBL:ENSG00000282608 ADORA3
ENSEMBL_homo_sapiens_GENE:ENSG00000282608.2 ADORA3
HGNC:268 ADORA3
KEGG Gene (Homo sapiens):140 ADORA3
Monarch:140 ADORA3
NCBI Gene:140 ADORA3
OMIM:600445 ADORA3
Reference Transcript
RefSeq:NM_000677.3 ADORA3
Other Identifiers
11726823_at
140
206171_PM_at
206171_at
2428000
2428001
2428002
2428003
2428006
2428007
2428008
2428009
36255_at
A_23_P137931
GE79503
GO:0001609
GO:0001973
GO:0003013
GO:0004930
GO:0005886
GO:0006351
GO:0006355
GO:0006954
GO:0007165
GO:0007186
GO:0007190
GO:0008016
GO:0008285
GO:0009611
GO:0014061
GO:0016020
GO:0023052
GO:0030336
GO:0030425
GO:0032088
GO:0042734
GO:0045202
GO:0048870
GO:0050896
GO:0060089
GO:0098685
GO:0099171
GO:0110165
HMNXSV003018257
ILMN_1730710
L77730_at
PH_hs_0000033
PH_hs_0031122
g6031156_3p_at
Participates
as a member of
ADORA1,3 [plasma membrane] (Homo sapiens)
Inferred To
ADORA3 [plasma membrane]
(Bos taurus)
ADORA3 [plasma membrane]
(Caenorhabditis elegans)
ADORA3 [plasma membrane]
(Canis familiaris)
ADORA3 [plasma membrane]
(Gallus gallus)
TMIGD3 [plasma membrane]
(Sus scrofa)
gtr-1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of ADORA3 [plasma membrane]
(Caenorhabditis elegans)
Adora3 [plasma membrane]
(Mus musculus)
Adora3 [plasma membrane]
(Rattus norvegicus)
AdoR [plasma membrane]
(Drosophila melanogaster)
ador-1 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_000668.1
ZINC - World Drugs
AA3R_HUMAN
Guide to Pharmacology - Targets
21
OpenTargets
ENSG00000282608
ZINC - FDA approved
AA3R_HUMAN
ZINC - Substances
AA3R_HUMAN
ZINC target
P0DMS8
ZINC - Biogenic
AA3R_HUMAN
PRO
P0DMS8
ZINC - Investigational
AA3R_HUMAN
ZINC - Metabolites
AA3R_HUMAN
HPA
ENSG00000282608-ADORA3
GeneCards
P0DMS8
Ensembl
ENST00000241356
,
ENSP00000241356
,
ENSG00000282608
Pharos - Targets
P0DMS8
ZINC - Predictions - Purchasable
AA3R_HUMAN
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