Ligation of DNA and formation of Holliday structures following repair synthesis

Stable Identifier
R-HSA-5693539
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Ligation of the crossed-strand intermediate results in the formation of double Holliday junctions with two crossovers. In humans, the identity of the ligase activity involved in this process is not known (reviewed by Ciccia and Elledge 2010).

Literature References
PubMed ID Title Journal Year
20965415 The DNA damage response: making it safe to play with knives

Ciccia, A, Elledge, SJ

Mol. Cell 2010
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created