HSD17B11 dehydrogenates EST17b to E1

Stable Identifier
R-HSA-5693390
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Estradiol 17-beta-dehydrogenase 11 (HSD17B11) may participate in androgen metabolism during steroidogenesis where it dehydrogenates estradiol-17-beta (EST17b) to estrone (E1) (Chai et al. 2003).

Literature References
PubMed ID Title Journal Year
12697717 17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells

Chai, Z, Brereton, P, Suzuki, T, Sasano, H, Obeyesekere, V, Escher, G, Saffery, R, Fuller, P, Enriquez, C, Krozowski, Z

Endocrinology 2003
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
estradiol 17-beta-dehydrogenase activity of HSD17B11 [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
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Reviewed
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