CDC14A,B dephosphorylate p-3S,T MAPK6

Stable Identifier
R-HSA-5692754
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CDC14A,B dephosphorylate p-3S,T MAPK6
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

CDC14A and B bind to MAPK6 and antagonize the CDK1-dependent phosphorylation of the C-terminal extension during mitosis (Tanguay et al, 2010; Hansen et al, 2008).

Literature References
Participants
Input
Output
Participates
as an event of
Catalyst Activity

protein serine/threonine phosphatase activity of p-3S,T MAPK6:CDC14A,B [nucleoplasm]

Physical Entity
p-3S,T MAPK6:CDC14A,B [nucleoplasm] (Homo sapiens)
Activity
protein serine/threonine phosphatase activity (GO:0004722)
Orthologous Events
CDC14A,B dephosphorylate p-3S,T MAPK6 (Bos taurus)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Canis familiaris)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Danio rerio)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Gallus gallus)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Mus musculus)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Rattus norvegicus)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Saccharomyces cerevisiae)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Schizosaccharomyces pombe)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Sus scrofa)
CDC14A,B dephosphorylate p-3S,T MAPK6 (Xenopus tropicalis)
Authored
Meloche, S  (2015-05-12)
Reviewed
Soulez, M  (2015-05-12)
Mathien, S  (2015-05-12)
Meloche, S  (2015-05-12)
Created
Rothfels, K  (2015-05-13)
Cite Us!