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ISCA1 [mitochondrial matrix]
Stable Identifier
R-HSA-5691212
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Iron-sulfur cluster assembly 1 homolog, mitochondrial, ISCA1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
Transfer of Fe-S clusters to SDHB (Homo sapiens)
ISCA1:ISCA2 [mitochondrial matrix] (Homo sapiens)
ISCA1 [mitochondrial matrix] (Homo sapiens)
ISCA1:ISCA2:4Fe-4S [mitochondrial matrix] (Homo sapiens)
ISCA1:ISCA2 [mitochondrial matrix] (Homo sapiens)
ISCA1 [mitochondrial matrix] (Homo sapiens)
Mitochondrial iron-sulfur cluster biogenesis (Homo sapiens)
Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Homo sapiens)
ISCA1:ISCA2 [mitochondrial matrix] (Homo sapiens)
ISCA1 [mitochondrial matrix] (Homo sapiens)
ISCA1:ISCA2:4Fe-4S [mitochondrial matrix] (Homo sapiens)
ISCA1:ISCA2 [mitochondrial matrix] (Homo sapiens)
ISCA1 [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BUE6 ISCA1
Gene Names
ISCA1, HBLD2, GK004
Chain
transit peptide:1-12, chain:13-129
Reference Genes
BioGPS Gene:81689 ISCA1
COSMIC (genes):ISCA1 ISCA1
CTD Gene:81689 ISCA1
dbSNP Gene:81689 ISCA1
ENSEMBL:ENSG00000135070 ISCA1
HGNC:28660 ISCA1
KEGG:hsa:81689 ISCA1
Monarch:81689 ISCA1
NCBI Gene:81689 ISCA1
OMIM:611006 ISCA1
UCSC:Q9BUE6 ISCA1
Reference Transcript
RefSeq:NM_030940.3 ISCA1
Other Identifiers
11716466_s_at
11716467_x_at
11716468_s_at
17095450
209273_PM_s_at
209273_s_at
209274_PM_s_at
209274_s_at
221425_PM_s_at
221425_s_at
2575391
2575396
2859282
2859283
2859284
2859285
2859286
3212951
3212952
3212953
3212954
3212955
3212956
3212957
3212958
3212959
3212960
3212961
3212962
3212963
3212968
3212969
3212970
3212971
3826045
3856443
3856446
41147_at
52639_at
8112331
8162142
81689
A_24_P387609
A_32_P25253
GE54310
GE894426
GO:0005515
GO:0005737
GO:0005739
GO:0005759
GO:0016226
GO:0043226
GO:0046872
GO:0051536
GO:0051537
GO:0051604
GO:0097428
GO:0120510
HMNXSV003013959
Hs.177776.0.S1_3p_a_at
ILMN_1672024
ILMN_1675421
ILMN_1715931
ILMN_2219556
ILMN_2341711
PH_hs_0036055
TC05001402.hg
TC09002895.hg
g12803678_3p_a_at
g13569910_3p_s_at
Participates
as a component of
ISCA1:ISCA2 [mitochondrial matrix] (Homo sapiens)
Inferred To
ISCA1 [mitochondrial matrix]
(Bos taurus)
ISCA1 [mitochondrial matrix]
(Caenorhabditis elegans)
ISCA1 [mitochondrial matrix]
(Canis familiaris)
ISCA1 [mitochondrial matrix]
(Dictyostelium discoideum)
ISCA1 [mitochondrial matrix]
(Drosophila melanogaster)
ISCA1 [mitochondrial matrix]
(Gallus gallus)
ISCA1 [mitochondrial matrix]
(Mus musculus)
ISCA1 [mitochondrial matrix]
(Plasmodium falciparum)
ISCA1 [mitochondrial matrix]
(Rattus norvegicus)
ISCA1 [mitochondrial matrix]
(Saccharomyces cerevisiae)
ISCA1 [mitochondrial matrix]
(Schizosaccharomyces pombe)
ISCA1 [mitochondrial matrix]
(Sus scrofa)
Cross References
RefSeq
NP_112202.2
ENSEMBL
ENST00000375991
,
ENSP00000365159
OpenTargets
ENSG00000135070
HPA
ENSG00000135070-ISCA1
PRO
Q9BUE6
Pharos - Targets
Q9BUE6
Orphanet
ISCA1
HMDB Protein
HMDBP08675
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96RU8 TRIB1
1
TRIB1 [cytosol]
(R-HSA-9621338)
0.527
2
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