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USP21 [nucleoplasm]
Stable Identifier
R-HSA-5690190
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin carboxyl-terminal hydrolase 21, USP23, Deubiquitinating enzyme 21
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)
USP16,USP21 [nucleoplasm] (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP16,USP21:Ub-histone H2A [nucleoplasm] (Homo sapiens)
USP16,USP21 [nucleoplasm] (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP16,USP22:Histone H2A [nucleoplasm] (Homo sapiens)
USP16,USP21 [nucleoplasm] (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP21 deubiquitinates GATA3,IL33 (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP21:GATA3,IL33 [nucleoplasm] (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP21:PolyUb-GATA3,PolyUb-IL33 [nucleoplasm] (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
USP21 deubiquitinates RIPK1,DDX58 (Homo sapiens)
USP21 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UK80 USP21
Gene Names
USP21, USP23, PP1490
Chain
chain:1-565
Reference Genes
COSMIC (genes):USP21 USP21
ENSEMBL:ENSG00000143258 USP21
HGNC:12620 USP21
UCSC:Q9UK80 USP21
Other Identifiers
11739259_a_at
11756321_x_at
16672754
218367_3p_x_at
218367_PM_x_at
218367_x_at
232219_PM_x_at
232219_x_at
234735_PM_s_at
234735_s_at
2363443
2363445
2363446
2363447
2363449
2363450
2363451
2363452
2363453
2363454
2363455
2363456
2363457
2363458
2363459
2363460
2363462
2363463
2363464
2363465
2363466
2363467
2363468
2363469
2363470
2363471
2363472
2363473
2363474
2363475
2363476
2363477
2363478
2363479
2363480
2363481
2363482
2363483
2363485
2363486
2363487
2363488
2529852
27005
46292_at
7906671
A_14_P118597
A_23_P126689
A_24_P139620
GE54999
GO:0003713
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006325
GO:0006355
GO:0006508
GO:0008233
GO:0008234
GO:0016579
GO:0016787
GO:0019784
GO:0043226
GO:0045815
GO:0045893
GO:0046872
GO:0060090
GO:0140096
GO:0140110
HMNXSV003021280
HMNXSV003051761
ILMN_1651370
ILMN_1780887
ILMN_2349006
PH_hs_0030956
TC01001379.hg
g6912741_3p_a_at
g6912741_3p_s_at
Participates
as a member of
USP16,USP21 [nucleoplasm] (Homo sapiens)
as a component of
USP21:GATA3,IL33 [nucleoplasm] (Homo sapiens)
USP21:PolyUb-GATA3,PolyUb-IL33 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
USP21 [cytosol]
Inferred To
USP21 [nucleoplasm]
(Bos taurus)
USP21 [nucleoplasm]
(Caenorhabditis elegans)
USP21 [nucleoplasm]
(Canis familiaris)
USP21 [nucleoplasm]
(Dictyostelium discoideum)
USP21 [nucleoplasm]
(Drosophila melanogaster)
USP21 [nucleoplasm]
(Mus musculus)
USP21 [nucleoplasm]
(Rattus norvegicus)
USP21 [nucleoplasm]
(Sus scrofa)
usp21 [nucleoplasm]
(Xenopus tropicalis)
Cross References
Guide to Pharmacology - Targets
3223
ENSEMBL
ENSP00000356981
,
ENSP00000356980
,
ENSP00000289865
,
ENST00000368001
,
ENST00000289865
,
ENST00000368002
OpenTargets
ENSG00000143258
IntEnz
3.4.19.12
HPA
ENSG00000143258-USP21
ZINC - Substances
UBP21_HUMAN
ZINC target
Q9UK80
PRO
Q9UK80
Pharos - Targets
Q9UK80
HMDB Protein
HMDBP11567
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