Reactome | USP16,USP21 deubiquitinate Histone H2A

USP16,USP21 deubiquitinate Histone H2A

Stable Identifier

R-HSA-5690157

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

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USP16 and USP21 can associate with and deubiquitinate H2A (Joo et al. 2007, Zhang et al. 2014, Nakagawa et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
25305019	The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage Yang, H, Zhang, Z, Wang, H	J. Biol. Chem.	2014
18172164	Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation Kajitani, T, Koji, T, Ohdan, H, Nakagawa, T, Ito, T, Ikura, T, Matsuyama, T, Masuko, N, Muramatsu, M, Togo, S, Hishikawa, Y	Genes Dev.	2008