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USP5 [cytosol]
Stable Identifier
R-HSA-5690104
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin carboxyl-terminal hydrolase 5 ecNumber3.4.19.12/ecNumber, UBP5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP5 cleaves polyubiquitin (Homo sapiens)
USP5 [cytosol] (Homo sapiens)
USP5:PolyUb [cytosol] (Homo sapiens)
USP5 [cytosol] (Homo sapiens)
USP5:Ub [cytosol] (Homo sapiens)
USP5 [cytosol] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
OTULIN,USP5 cleaves UBB yielding ubiquitin (Homo sapiens)
OTULIN,USP5 [cytosol] (Homo sapiens)
USP5 [cytosol] (Homo sapiens)
OTULIN,USP5 cleaves UBC yielding ubiquitin (Homo sapiens)
OTULIN,USP5 [cytosol] (Homo sapiens)
USP5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P45974 USP5
Gene Names
USP5, ISOT
Chain
initiator methionine:1, chain:2-858
Reference Genes
BioGPS Gene:8078 USP5
COSMIC (genes):USP5 USP5
CTD Gene:8078 USP5
dbSNP Gene:8078 USP5
ENSEMBL:ENSG00000111667 USP5
HGNC:12628 USP5
KEGG:hsa:8078 USP5
Monarch:8078 USP5
NCBI Gene:8078 USP5
OMIM:601447 USP5
UCSC:P45974 USP5
Reference Transcript
RefSeq:NM_003481.3 USP5
RefSeq:NM_001098536.2 USP5
Participates
as a component of
USP5:Ub [cytosol] (Homo sapiens)
USP5:PolyUb [cytosol] (Homo sapiens)
as a member of
OTULIN,USP5 [cytosol] (Homo sapiens)
Inferred To
Usp5 [cytosol]
(Drosophila melanogaster)
Usp5 [cytosol]
(Mus musculus)
Usp5 [cytosol]
(Rattus norvegicus)
USP5 [cytosol]
(Bos taurus)
USP5 [cytosol]
(Canis familiaris)
USP5 [cytosol]
(Gallus gallus)
USP5 [cytosol]
(Sus scrofa)
usp-5 [cytosol]
(Caenorhabditis elegans)
usp5 [cytosol]
(Danio rerio)
ubpA [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001092006.1
,
NP_003472.2
Guide to Pharmacology - Targets
2431
ENSEMBL
ENST00000229268
,
ENSP00000229268
,
ENST00000389231
,
ENSG00000111667
,
ENSP00000373883
OpenTargets
ENSG00000111667
ZINC - Substances
UBP5_HUMAN
ZINC target
P45974
PRO
P45974
GlyGen
P45974
PDB
7MS7
,
7MS5
,
6P9G
,
2G43
,
7MS6
,
6DXT
,
3IHP
,
2DAG
,
6NFT
,
2DAK
,
2G45
,
6DXH
IntEnz
3.4.19.12
GeneCards
USP5
HPA
ENSG00000111667-USP5
Pharos - Targets
P45974
ZINC - Predictions - Purchasable
UBP5_HUMAN
HMDB Protein
HMDBP10125
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75528 TADA3
1
TADA3 [nucleoplasm]
(R-HSA-3322966)
0.508
2
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