Reactome | USP5 [cytosol]

USP5 [cytosol]

Stable Identifier

R-HSA-5690104

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin carboxyl-terminal hydrolase 5 ecNumber3.4.19.12/ecNumber, UBP5_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P45974 USP5

Gene Names

USP5, ISOT

Chain

initiator methionine:1, chain:2-858

Reference Genes

BioGPS Gene:8078 USP5

COSMIC (genes):USP5 USP5

CTD Gene:8078 USP5

dbSNP Gene:8078 USP5

ENSEMBL:ENSG00000111667 USP5

ENSEMBL:ENSG00000111667.14 USP5

HGNC:12628 USP5

KEGG Gene (Homo sapiens):8078 USP5

Monarch:8078 USP5

NCBI Gene:8078 USP5

OMIM:601447 USP5

UCSC:P45974 USP5

Reference Transcript

Other Identifiers

11721016_a_at

16747501

206031_PM_s_at

206031_s_at

3402900

3402901

3402903

3402904

3402907

3402909

3402910

3402912

3402913

3402915

3402916

3402917

3402918

3402919

3402922

3402924

3402925

3402927

3402929

3402931

3402932

3402933

3402934

34405_at

7953483

8078

A_23_P64954

GE62535

GO:0003824

GO:0004197

GO:0004843

GO:0005515

GO:0005634

GO:0005764

GO:0005773

GO:0005829

GO:0006508

GO:0006511

GO:0008233

GO:0008234

GO:0008270

GO:0016567

GO:0016579

GO:0016787

GO:0030163

GO:0032436

GO:0036211

GO:0043130

GO:0043226

GO:0046872

GO:0071108

GO:0140096

HMNXSV003042477

ILMN_1671494

PH_hs_0000428

TC12000095.hg

U47927_at

g4507854_3p_a_at

Participates

as a component of

as a member of

OTULIN,USP5 [cytosol] (Homo sapiens)

Inferred To

Usp5 [cytosol] (Rattus norvegicus)

USP5 [cytosol] (Bos taurus)

USP5 [cytosol] (Caenorhabditis elegans)

USP5 [cytosol] (Canis familiaris)

USP5 [cytosol] (Danio rerio)

USP5 [cytosol] (Drosophila melanogaster)

USP5 [cytosol] (Gallus gallus)

USP5 [cytosol] (Mus musculus)

USP5 [cytosol] (Sus scrofa)

ubpA [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001092006.1, NP_003472.2

Guide to Pharmacology - Targets

2431

OpenTargets

ENSG00000111667

ZINC - Substances

UBP5_HUMAN

ZINC target

P45974

PRO

P45974

PDB

2G43, 6DXT, 6NFT, 3IHP, 7MS7, 2DAK, 6P9G, 2G45, 6DXH, 7MS6, 7MS5, 2DAG

HPA

ENSG00000111667-USP5

GeneCards

P45974

Ensembl

ENST00000229268, ENSG00000111667, ENSP00000373883, ENSP00000229268, ENST00000389231

Pharos - Targets

P45974

ZINC - Predictions - Purchasable

UBP5_HUMAN

HMDB Protein

HMDBP10125

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75528 TADA3	1	TADA3 [nucleoplasm] (R-HSA-3322966)	0.508	2