Reactome | ACOT7 [cytosol]

ACOT7 [cytosol]

Stable Identifier

R-HSA-5690040

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Cytosolic acyl coenzyme A thioester hydrolase ecNumber3.1.2.2/ecNumber, BACH_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00154 ACOT7

Gene Names

ACOT7, BACH

Chain

chain:1-380

Reference Genes

BioGPS Gene:11332 ACOT7

COSMIC (genes):ACOT7 ACOT7

CTD Gene:11332 ACOT7

dbSNP Gene:11332 ACOT7

ENSEMBL:ENSG00000097021 ACOT7

HGNC:24157 ACOT7

KEGG:hsa:11332 ACOT7

Monarch:11332 ACOT7

NCBI Gene:11332 ACOT7

OMIM:602587 ACOT7

UCSC:O00154 ACOT7

Reference Transcript

Participates

as a component of

ACOT7 hexamer [cytosol] (Homo sapiens)

Inferred To

ACOT7 [cytosol] (Bos taurus)

ACOT7 [cytosol] (Canis familiaris)

ACOT7 [cytosol] (Gallus gallus)

ACOT7 [cytosol] (Sus scrofa)

Acot7 [cytosol] (Mus musculus)

Acot7 [cytosol] (Rattus norvegicus)

acot7 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_863654.1, NP_863656.1, NP_863655.1, NP_009205.3

ENSEMBL

ENST00000418124, ENSP00000402532, ENSP00000476610, ENSP00000367076, ENST00000377860, ENSP00000354615, ENST00000377842, ENST00000608083, ENST00000377855, ENST00000377845, ENSP00000367091, ENSG00000097021, ENSP00000367086, ENSP00000367073, ENST00000361521

OpenTargets

ENSG00000097021

GeneCards

ACOT7

HPA

ENSG00000097021-ACOT7

PRO

O00154

Pharos - Targets

O00154

GlyGen

O00154

HMDB Protein

HMDBP01046

PDB

2QQ2

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9HCK8 CHD8	1	CHD8 [nucleoplasm] (R-HSA-3221598)	0.499	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	8

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