Reactome | NDUFAF2 [mitochondrial inner membrane]

NDUFAF2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5689129

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Mimitin, mitochondrial, MIMIT_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N183 NDUFAF2

Gene Names

NDUFAF2, NDUFA12L

Chain

transit peptide:1-, chain:-169

Reference Genes

BioGPS Gene:91942 NDUFAF2

COSMIC (genes):NDUFAF2 NDUFAF2

CTD Gene:91942 NDUFAF2

dbSNP Gene:91942 NDUFAF2

ENSEMBL:ENSG00000164182 NDUFAF2

HGNC:28086 NDUFAF2

KEGG:hsa:91942 NDUFAF2

Monarch:91942 NDUFAF2

NCBI Gene:91942 NDUFAF2

OMIM:609653 NDUFAF2

UCSC:Q8N183 NDUFAF2

Reference Transcript

RefSeq:NM_174889.4 NDUFAF2

Other Identifiers

11758314_s_at

16985079

228355_PM_s_at

228355_s_at

2542974

2542975

2542976

2542977

2811248

2811249

2811250

2811251

2811258

2811263

2811265

2811267

2811270

2811271

2811273

2811274

2811275

52070_at

8050591

8105499

91942

A_19_P00810523

A_23_P345942

A_23_P360983

A_32_P49555

GE478803

GO:0005515

GO:0005739

GO:0005743

GO:0016020

GO:0032981

GO:0043226

GO:0044877

GO:0061179

GO:0065003

HMNXSV003019619

Hs.42758.0.A1_3p_a_at

ILMN_1682857

PH_hs_0027483

PH_hs_0033707

TC05000260.hg

TC05002395.hg

Participates

as an output of

The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Homo sapiens)

as an input of

NDUF subunits bind to form the FP subcomplex (Homo sapiens)

as a component of

FP subcomplex [mitochondrial inner membrane] (Homo sapiens)

Inferred To

NDUFAF2 [mitochondrial inner membrane] (Bos taurus)

NDUFAF2 [mitochondrial inner membrane] (Caenorhabditis elegans)

NDUFAF2 [mitochondrial inner membrane] (Canis familiaris)

NDUFAF2 [mitochondrial inner membrane] (Gallus gallus)

NDUFAF2 [mitochondrial inner membrane] (Sus scrofa)

Ghost homologue of NDUFAF2 [mitochondrial inner membrane] (Danio rerio)

Ndufaf2 [mitochondrial inner membrane] (Mus musculus)

Ndufaf2 [mitochondrial inner membrane] (Rattus norvegicus)

ndufaf2 [mitochondrial inner membrane] (Xenopus tropicalis)

Dmel\CG43346 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

ENSEMBL

ENST00000296597, ENSP00000296597

OpenTargets

ENSG00000164182

HPA

ENSG00000164182-NDUFAF2

PRO

Q8N183

Pharos - Targets

Q8N183

GlyGen

Q8N183

Orphanet

NDUFAF2

HMDB Protein

HMDBP08889

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5BJF2 SGMR2			0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:O43169 CYB5B	2	CYB5B [endoplasmic reticulum membrane] (R-HSA-9842695) CYB5B [mitochondrial outer membrane] (R-HSA-8943390)	0.556	3
UniProt:Q9NZD8 SPG21			0.556	3
UniProt:Q5SNT2-2 TMEM201			0.556	3
UniProt:B2RUZ4 SMIM1			0.556	3
UniProt:Q9UBY5 LPAR3	1	LPAR3 [plasma membrane] (R-HSA-419379)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:O43561-2 LAT	2	p-5Y-LAT-2 [plasma membrane] (R-HSA-2396597) LAT-2 [plasma membrane] (R-HSA-2396548)	0.556	3
UniProt:Q9NTU7 CBLN4			0.527	2
UniProt:P0DTD1-PRO_0000449625 REP			0.527	2

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