ATXN3 binds polyUb-PARK2

Stable Identifier
R-HSA-5689085
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Ataxin-3 (ATXN3) binds to poly-ubiquitinated Parkin (PARK2) but not unubiquitinated or mono-ubiquitinated PARK2 (Durcan et al. 2011).

Literature References
PubMed ID Title Journal Year
20940148 The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability

Durcan, TM, Kontogiannea, M, Thorarinsdottir, T, Fallon, L, Williams, AJ, Djarmati, A, Fantaneanu, T, Paulson, HL, Fon, EA

Hum. Mol. Genet. 2011
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