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RNF14 [cytosol]
Stable Identifier
R-HSA-5688974
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase RNF14 ecNumber6.3.2.-/ecNumber, RNF14_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
RNF14 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UBS8 RNF14
Gene Names
RNF14, ARA54, HRIHFB2038
Chain
chain:1-474
Reference Genes
BioGPS Gene:9604 RNF14
COSMIC (genes):RNF14 RNF14
CTD Gene:9604 RNF14
dbSNP Gene:9604 RNF14
ENSEMBL:ENSG00000013561 RNF14
ENSEMBL_homo_sapiens_GENE:ENSG00000013561.18 RNF14
HGNC:10058 RNF14
KEGG Gene (Homo sapiens):9604 RNF14
Monarch:9604 RNF14
NCBI Gene:9604 RNF14
OMIM:605675 RNF14
UCSC:Q9UBS8 RNF14
Reference Transcript
RefSeq:NM_183400.2 RNF14
RefSeq:NM_001201365.1 RNF14
RefSeq:XM_017010072.1 RNF14
RefSeq:NM_183399.2 RNF14
RefSeq:XM_005268539.2 RNF14
RefSeq:XM_005268540.3 RNF14
RefSeq:XM_017010071.1 RNF14
RefSeq:XM_005268537.2 RNF14
RefSeq:XM_017010070.1 RNF14
RefSeq:NM_183398.2 RNF14
RefSeq:NM_004290.4 RNF14
RefSeq:XM_005268536.2 RNF14
RefSeq:XM_011537714.2 RNF14
RefSeq:NM_183401.2 RNF14
RefSeq:XM_005268541.3 RNF14
Other Identifiers
11719392_a_at
11748139_a_at
16990423
201823_PM_s_at
201823_s_at
201824_PM_at
201824_at
243345_PM_at
243345_at
2833028
2833030
2833031
2833032
2833035
2833036
2833037
2833038
2833039
2833040
2833042
2833043
2833045
2833046
2833047
2833048
2833049
2833050
2833051
2833052
2833053
2833054
33343_at
8108847
9604
A_23_P255317
A_24_P132039
A_24_P69150
A_32_P222521
GE61484
GO:0000151
GO:0000209
GO:0003713
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005840
GO:0006351
GO:0006355
GO:0006357
GO:0006511
GO:0007165
GO:0008270
GO:0016567
GO:0016740
GO:0019538
GO:0019787
GO:0022626
GO:0023052
GO:0030163
GO:0030521
GO:0031624
GO:0032436
GO:0036211
GO:0043226
GO:0045893
GO:0046872
GO:0050681
GO:0060765
GO:0060828
GO:0061630
GO:0072344
GO:0085020
GO:0140096
GO:0140110
HMNXSV003049782
Hs.170926.0.A1_3p_at
ILMN_1714461
ILMN_2351241
PH_hs_0022822
TC05000776.hg
g4757761_3p_a_at
g5019617_3p_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
RNF14 [cytosol]
(Bos taurus)
RNF14 [cytosol]
(Caenorhabditis elegans)
RNF14 [cytosol]
(Canis familiaris)
RNF14 [cytosol]
(Danio rerio)
RNF14 [cytosol]
(Dictyostelium discoideum)
RNF14 [cytosol]
(Gallus gallus)
RNF14 [cytosol]
(Mus musculus)
RNF14 [cytosol]
(Rattus norvegicus)
RNF14 [cytosol]
(Saccharomyces cerevisiae)
RNF14 [cytosol]
(Schizosaccharomyces pombe)
RNF14 [cytosol]
(Sus scrofa)
rnf14.2 [cytosol]
(Xenopus tropicalis)
Homologues of RNF14 [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
XP_005268594.1
,
NP_004281.1
,
NP_899647.1
,
XP_005268598.1
,
XP_016865561.1
,
XP_016865559.1
,
XP_005268597.1
,
XP_016865560.1
,
XP_005268593.1
,
NP_899646.1
,
XP_005268596.1
,
NP_899645.1
,
NP_001188294.1
,
XP_011536016.1
,
NP_899648.1
OpenTargets
ENSG00000013561
GeneCards
Q9UBS8
HPA
ENSG00000013561-RNF14
Ensembl
ENST00000347642
,
ENST00000394514
,
ENSP00000348462
,
ENST00000356143
,
ENSP00000324956
,
ENSP00000378022
,
ENSP00000378028
,
ENST00000394520
,
ENST00000394519
,
ENSP00000378027
,
ENSG00000013561
PRO
Q9UBS8
Pharos - Targets
Q9UBS8
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P51668 UBE2D1
3
UBE2D1 [cytosol]
(R-HSA-174236)
UBE2D1 [nucleoplasm]
(R-HSA-174197)
Ub-C85-UBE2D1 [cytosol]
(R-HSA-8864160)
0.666
4
UniProt:P10275 AR
4
PolyUb-AR [nucleoplasm]
(R-HSA-6782984)
monoSUMO1-K386,520-AR [nucleoplasm]
(R-HSA-4090320)
AR [nucleoplasm]
(R-HSA-446174)
AR [cytosol]
(R-HSA-5618082)
0.499
2
UniProt:P20823 HNF1A
1
HNF1A [nucleoplasm]
(R-HSA-3004629)
0.482
2
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