Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TRIM71 [cytosol]
Stable Identifier
R-HSA-5688972
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRIM71 ecNumber6.3.2.-/ecNumber, LIN41_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRIM71 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q2Q1W2 TRIM71
Gene Names
TRIM71, LIN41
Chain
initiator methionine:, chain:2-868
Reference Genes
BioGPS Gene:131405 TRIM71
COSMIC (genes):TRIM71 TRIM71
CTD Gene:131405 TRIM71
dbSNP Gene:131405 TRIM71
ENSEMBL:ENSG00000206557 TRIM71
ENSEMBL_homo_sapiens_GENE:ENSG00000206557.6 TRIM71
ENSEMBL_homo_sapiens_GENE:ENSG00000291501.1 TRIM71
HGNC:32669 TRIM71
KEGG Gene (Homo sapiens):131405 TRIM71
Monarch:131405 TRIM71
NCBI Gene:131405 TRIM71
OMIM:618570 TRIM71
UCSC:Q2Q1W2 TRIM71
Reference Transcript
RefSeq:NM_001039111.2 TRIM71
Other Identifiers
11734427_at
11763966_at
131405
16938701
231310_PM_at
231310_at
2616079
2616094
2616096
2616105
2616106
2616111
2616112
2616114
2616116
2616118
2616120
2616122
2616124
2616126
2616128
3254695
3515452
76082_at
8078435
82216_at
A_32_P221429
A_33_P3354429
GE487466
GE548084
GE868263
GO:0000082
GO:0000209
GO:0000278
GO:0000932
GO:0001843
GO:0003723
GO:0003824
GO:0004842
GO:0005515
GO:0005737
GO:0008270
GO:0008543
GO:0010608
GO:0016071
GO:0016567
GO:0016740
GO:0017148
GO:0021915
GO:0023052
GO:0030163
GO:0030371
GO:0031047
GO:0035196
GO:0035198
GO:0035278
GO:0036211
GO:0043161
GO:0043226
GO:0045182
GO:0046872
GO:0048856
GO:0051246
GO:0051865
GO:0060964
GO:0061158
GO:0061630
GO:0071310
GO:0072089
GO:0140096
GO:2000177
GO:2000637
HMNXSV003007467
Hs.113170.0.A1_3p_at
ILMN_1714774
ILMN_1828120
ILMN_2225061
PH_hs_0006231
PH_hs_0034445
TC03000163.hg
TC03002274.hg
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
trim71 [cytosol]
(Xenopus tropicalis)
TRIM71 [cytosol]
(Bos taurus)
TRIM71 [cytosol]
(Canis familiaris)
TRIM71 [cytosol]
(Danio rerio)
TRIM71 [cytosol]
(Gallus gallus)
TRIM71 [cytosol]
(Mus musculus)
TRIM71 [cytosol]
(Rattus norvegicus)
TRIM71 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001034200.1
OpenTargets
ENSG00000206557
GeneCards
Q2Q1W2
HPA
ENSG00000206557-TRIM71
Ensembl
ENST00000383763
,
ENSG00000206557
,
ENSP00000373272
PRO
Q2Q1W2
Pharos - Targets
Q2Q1W2
PDB
7QRX
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A1L190 SYCE3
1
SYCE3 [nucleoplasm]
(R-HSA-8867779)
0.527
3
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text