Reactome | TRIM39 [cytosol]

TRIM39 [cytosol]

Stable Identifier

R-HSA-5688971

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase TRIM39 ecNumber6.3.2.-/ecNumber, TRI39_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HCM9 TRIM39

Gene Names

TRIM39, RNF23, TFP

Chain

chain:1-518

Reference Genes

BioGPS Gene:56658 TRIM39

COSMIC - genes:TRIM39 TRIM39

CTD Gene:56658 TRIM39

dbSNP Gene:56658 TRIM39

ENSEMBL:ENSG00000204599 TRIM39

HGNC:10065 TRIM39

KEGG:hsa:56658 TRIM39

Monarch:56658 TRIM39

NCBI Gene:56658 TRIM39

OMIM:605700 TRIM39

UCSC:Q9HCM9 TRIM39

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

btr02 [cytosol] (Danio rerio)

RPP21 [cytosol] (Canis familiaris)

TRIM58 [cytosol] (Gallus gallus)

TRIM39 [cytosol] (Bos taurus)

TRIM39 [cytosol] (Caenorhabditis elegans)

TRIM39 [cytosol] (Mus musculus)

TRIM39 [cytosol] (Rattus norvegicus)

TRIM39 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_001356452.1, NP_001356451.1, NP_001356450.1, NP_067076.2, NP_742013.1

OpenTargets

ENSG00000204599

ENSEMBL

ENST00000458607, ENSP00000398355, ENST00000451715, ENST00000452705, ENSP00000412743, ENSP00000397043, ENST00000424575, ENSP00000373096, ENSP00000392130, ENST00000549841, ENST00000400644, ENSP00000373095, ENSP00000379796, ENST00000430502, ENSG00000226437, ENST00000547030, ENSG00000230308, ENST00000419790, ENST00000438076, ENST00000451132, ENST00000433900, ENST00000426469, ENSG00000224994, ENSP00000391917, ENSP00000365844, ENST00000443109, ENST00000440117, ENSP00000409902, ENST00000438859, ENST00000450778, ENSP00000450288, ENST00000396548, ENSP00000383486, ENSP00000448572, ENST00000376659, ENSG00000232839, ENSP00000401184, ENSP00000449847, ENST00000376656, ENSP00000379797, ENSP00000448462, ENSP00000398956, ENSP00000415259, ENSP00000373097, ENST00000552337, ENST00000449318, ENSP00000414525, ENSP00000404904, ENSP00000387445, ENST00000414015, ENST00000383601, ENSG00000229929, ENSP00000394353, ENSP00000404340, ENSP00000396986, ENST00000446397, ENST00000550282, ENST00000431272, ENSP00000411582, ENST00000552520, ENSP00000365847, ENSP00000449272, ENSP00000379800, ENST00000396551, ENST00000383603, ENST00000548002, ENST00000383602, ENSP00000411949, ENSP00000401071, ENST00000445206, ENST00000413715, ENST00000396547, ENSP00000447835, ENSG00000204599, ENSP00000389852, ENSG00000206495, ENSP00000389198

GeneCards

TRIM39

HPA

ENSG00000204599-TRIM39

PRO

Q9HCM9

Pharos - Targets

Q9HCM9

PDB

2DID, 2DIF, 2ECJ

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P51668 UBE2D1	4	UBE2D1 [cytosol] (R-HSA-174236) UBE2D1 [nucleoplasm] (R-HSA-174197) Ub-C85-UBE2D1 [cytosol] (R-HSA-8864160) Ub-C85-UBE2D1 [nucleoplasm] (R-HSA-8937534)	0.8	6
UniProt:P61077 UBE2D3	3	Ub-C85-UBE2D3 [cytosol] (R-HSA-8864191) UBE2D3 [cytosol] (R-HSA-934630) UBE2D3 [nucleoplasm] (R-HSA-205341)	0.8	6
UniProt:O00233 PSMD9	1	PSMD9 [cytosol] (R-HSA-68810)	0.666	4
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.666	4
UniProt:P19474 TRIM21	1	TRIM21 [cytosol] (R-HSA-976051)	0.666	4
UniProt:Q04323 UBXN1	2	UBXN1 [cytosol] (R-HSA-8850588) UBXN1 [nucleoplasm] (R-HSA-9707052)	0.556	3
UniProt:P60900 PSMA6	2	PSMA6 [cytosol] (R-HSA-68734) PSMA6 [nucleoplasm] (R-HSA-174314)	0.556	3
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.553	2

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