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ACSS2 [mitochondrial matrix]
Stable Identifier
R-HSA-5688311
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
Acetyl-coenzyme A synthetase, cytoplasmic , Acetate--CoA ligase, Acyl-activating enzyme, Acetyl-CoA synthetase, ACS, AceCS
Locations in the PathwayBrowser
Expand all
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Homo sapiens)
ACCS2,GLUD,IDH2,SOD2 [mitochondrial matrix] (Homo sapiens)
ACSS2 [mitochondrial matrix] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
10843999
Molecular characterization of human acetyl-CoA synthetase, an enzyme regulated by sterol regulatory element-binding proteins.
Goldstein, JL
,
Luong, A
,
Hannah, VC
J Biol Chem
2000
External Reference Information
External Reference
UniProt:Q9NR19 ACSS2
Gene Names
ACSS2, ACAS2
Chain
chain:1-701
Reference Genes
BioGPS Gene:55902 ACSS2
COSMIC (genes):ACSS2 ACSS2
CTD Gene:55902 ACSS2
dbSNP Gene:55902 ACSS2
ENSEMBL:ENSG00000131069 ACSS2
ENSEMBL_homo_sapiens_GENE:ENSG00000131069.20 ACSS2
HGNC:15814 ACSS2
KEGG Gene (Homo sapiens):55902 ACSS2
Monarch:55902 ACSS2
NCBI Gene:55902 ACSS2
OMIM:605832 ACSS2
UCSC:Q9NR19 ACSS2
Reference Transcript
RefSeq:NM_018677.3 ACSS2
RefSeq:NM_001076552.2 ACSS2
Other Identifiers
11722346_a_at
11753466_a_at
16912975
234312_PM_s_at
234312_s_at
3883066
3883067
3883068
3883069
3883079
3883080
3883081
3883084
3883085
3883086
3883087
3883089
3883090
3883091
3883093
3883095
3883097
3883099
3883102
3883104
3883105
3883107
3883108
3883109
3883110
3883111
3883112
3883113
55902
57033_at
79418_at
8062041
A_14_P103550
A_24_P156295
GE55390
GE80338
GO:0000166
GO:0003682
GO:0003713
GO:0003824
GO:0003987
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005739
GO:0005759
GO:0005829
GO:0006069
GO:0006085
GO:0006091
GO:0006351
GO:0006355
GO:0006629
GO:0006790
GO:0007616
GO:0008610
GO:0016208
GO:0016405
GO:0016874
GO:0016878
GO:0019413
GO:0019427
GO:0019542
GO:0035066
GO:0036211
GO:0043226
GO:0045893
GO:0050218
GO:0050877
GO:0055086
GO:0140110
GO:1901135
HMNXSV003014234
Hs.14779.1.A1_3p_a_at
ILMN_1697510
ILMN_1714197
ILMN_2336595
PH_hs_0001395
Participates
as a member of
ACCS2,GLUD,IDH2,SOD2 [mitochondrial matrix] (Homo sapiens)
Other forms of this molecule
AcK-ACSS2 [mitochondrial matrix]
ACSS2 [cytosol]
Inferred To
acss2.1 [mitochondrial matrix]
(Xenopus tropicalis)
Acss2 [mitochondrial matrix]
(Rattus norvegicus)
acs-19 [mitochondrial matrix]
(Caenorhabditis elegans)
Homologues of ACSS2 [mitochondrial matrix]
(Saccharomyces cerevisiae)
AcCoAS [mitochondrial matrix]
(Drosophila melanogaster)
ACSS2 [mitochondrial matrix]
(Bos taurus)
ACSS2 [mitochondrial matrix]
(Canis familiaris)
ACSS2 [mitochondrial matrix]
(Dictyostelium discoideum)
ACSS2 [mitochondrial matrix]
(Gallus gallus)
ACSS2 [mitochondrial matrix]
(Mus musculus)
ACSS2 [mitochondrial matrix]
(Plasmodium falciparum)
ACSS2 [mitochondrial matrix]
(Saccharomyces cerevisiae)
ACSS2 [mitochondrial matrix]
(Schizosaccharomyces pombe)
ACSS2 [mitochondrial matrix]
(Sus scrofa)
Cross References
RefSeq
NP_001070020.2
,
NP_061147.1
Guide to Pharmacology - Targets
3128
OpenTargets
ENSG00000131069
HPA
ENSG00000131069-ACSS2
GeneCards
Q9NR19
Ensembl
ENST00000360596
,
ENSP00000353804
,
ENSP00000253382
,
ENSG00000131069
,
ENST00000253382
PRO
Q9NR19
Pharos - Targets
Q9NR19
HMDB Protein
HMDBP00037
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