SIRT5 deacetylates Cytochrome C

Stable Identifier
R-HSA-5688294
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial intermembrane space
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SIRT5 deacetylates Cytochrome C
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Sirtuin 5 has been shown to deacetylate Cytochrome C in the the mitochondrial intermembrane space (Schlicker et al. 2008). The functional significance of this is unknown (Bao & Sack 2010).

Literature References
PubMed ID Title Journal Year
18680753 Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

Schlicker, C, Gertz, M, Papatheodorou, P, Kachholz, B, Becker, CF, Steegborn, C

J. Mol. Biol. 2008
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
NAD-dependent protein deacetylase activity of SIRT5:Zn2+ [mitochondrial intermembrane space]
Physical Entity
SIRT5:Zn2+ [mitochondrial intermembrane space]
Activity
NAD-dependent protein deacetylase activity (0034979)
Orthologous Events
SIRT5 deacetylates Cytochrome C (Dictyostelium discoideum)
Authored
Jupe, S  (2015-04-15)
Reviewed
Haigis, M  (2017-02-01)
Created
Jupe, S  (2015-04-15)