Reactome | AcK-IDH2 [mitochondrial matrix]

AcK-IDH2 [mitochondrial matrix]

Stable Identifier

R-HSA-5688283

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Isocitrate dehydrogenase 2 (NADP), mitochondrial

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P48735 IDH2

Gene Names

IDH2

Chain

transit peptide:1-39, chain:40-452

Reference Genes

BioGPS Gene:3418 IDH2

COSMIC (genes):IDH2 IDH2

CTD Gene:3418 IDH2

dbSNP Gene:3418 IDH2

ENSEMBL:ENSG00000182054 IDH2

ENSEMBL:ENSG00000182054.10 IDH2

HGNC:5383 IDH2

KEGG Gene (Homo sapiens):3418 IDH2

Monarch:3418 IDH2

NCBI Gene:3418 IDH2

OMIM:147650 IDH2

UCSC:P48735 IDH2

Reference Transcript

Other Identifiers

11715536_a_at

11715537_x_at

11747814_a_at

11758723_at

16813270

210045_PM_at

210045_at

210046_PM_s_at

210046_s_at

32332_at

3418

3638756

3638761

3638762

3638763

3638765

3638766

3638767

3638769

3638772

3638774

3638775

3638777

3638778

3638783

3638788

3638789

79776_r_at

7991374

82364_at

A_23_P129209

GE59959

GO:0000287

GO:0003824

GO:0004450

GO:0005576

GO:0005615

GO:0005739

GO:0005759

GO:0005777

GO:0005829

GO:0005975

GO:0006091

GO:0006097

GO:0006099

GO:0006102

GO:0006103

GO:0006739

GO:0016491

GO:0016616

GO:0043226

GO:0046872

GO:0051287

GO:0055086

GO:0070062

HMNXSV003003114

Hs.5337.1.S2_3p_x_at

ILMN_1751753

PH_hs_0000548

TC15001841.hg

X69433_at

g1277202_3p_a_at

Participates

as a member of

Ack-ACCS2,AcK-GLUD,AcK-IDH2,Ack-SOD2 [mitochondrial matrix] (Homo sapiens)

Other forms of this molecule

IDH2 [mitochondrial matrix]

Inferred To

AcK-IDH2 [mitochondrial matrix] (Bos taurus)

AcK-IDH2 [mitochondrial matrix] (Caenorhabditis elegans)

AcK-IDH2 [mitochondrial matrix] (Canis familiaris)

AcK-IDH2 [mitochondrial matrix] (Gallus gallus)

AcK-IDH2 [mitochondrial matrix] (Mus musculus)

AcK-IDH2 [mitochondrial matrix] (Plasmodium falciparum)

AcK-IDH2 [mitochondrial matrix] (Rattus norvegicus)

AcK-IDH2 [mitochondrial matrix] (Sus scrofa)

AcK-IDH2 [mitochondrial matrix] (Xenopus tropicalis)

Modified Residues

Name

N6-acetyl-L-lysine at unknown position

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_001276839.1, NP_001277043.1, NP_002159.2

Guide to Pharmacology - Targets

2885

OpenTargets

ENSG00000182054

HPA

ENSG00000182054-IDH2

GeneCards

P48735

Ensembl

ENSP00000331897, ENSP00000446147, ENSG00000182054, ENST00000330062, ENST00000540499

PRO

P48735

Pharos - Targets

P48735

Orphanet

19506

HMDB Protein

HMDBP00896

PDB

6UJ7, 4JA8, 5I95, 6VFZ, 5SVN, 6ADI, 6UJ8, 5I96, 5SVO, 6UJ9, 5GIS