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p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
Stable Identifier
R-HSA-5687885
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Interleukin-17 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
MAP kinase activation (Homo sapiens)
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol] (Homo sapiens)
Participants
components
MAP3K8 [cytosol]
(Homo sapiens)
p-S927,S932-NFKB1(1-968) [cytosol]
(Homo sapiens)
TNIP2 [cytosol]
(Homo sapiens)
Participates
as an output of
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
Inferred To
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Bos taurus)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Canis familiaris)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Gallus gallus)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Mus musculus)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Sus scrofa)
p-S927,S932-NFKB1(1-968):MAP3K8:TNIP2 [cytosol]
(Xenopus tropicalis)
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